August 2012

Piramal Life Sciences Limited (PLSL) is an independent research-driven drug company that was recently demerged from Piramal Healthcare Limited (Formerly known as Nicholas Piramal India Limited). PLSL was formerly the NCE R&D division of NPIL.

The JNU campus is a microcosm of the Indian nation, drawing students from every nook and corner of the country and from every group and stratum of society.

About Author:
Tarika Priya
SLC's college of pharmacy. JNTUH
Hyderabad-500076
a4aryatarikapriya@gmail.com

1. Abstract
The aim of study was to screen the antibacterial and antifungal activities of methanol and ethanol extracts of fenugreek seed (Trigonella foenum). Crude extracts of the seeds with methanol and ethanol were screened for antibacterial activities against two gram positive pathogenic bacteria – Bacillus subtilis, Staphylococcus aureus and against two gram negative pathogenic bacteria – E.coli, klebsiella. The antibacterial activity was performed using cup-plate method. The extracts were prepared using soxhlet extraction method. Methanol extract showed activity against E.coli and Klebsiella were as ethanol extract showed activity against Staphylococcus and Bacillus spp.,

The anti fungal activity was also screened against Aspergillus niger. Both the extracts showed good activity against the fungi.
The results obtained in the present study suggest that the extracts revealed a significant scope to develop a novel broad spectrum of antibacterial herbal formulations.

About Authors:
Aadeshkumar*, Nishantkumar gupta, Dineshkumar gupta
Dept. of pharmacy
BIT meerut, UP
*adesh.adi.chaudhary@gmail.com

ABSTRACT
In recent years there has been a rapid increase in nanotechnology in the fields of medicine and more specifically in targeted drug delivery. The proprietary powder processing techniques use by nanotherapeutics improves the delivery of drug that can not normally taken orally.
It improves
·         Safety and efficacy of low molecular weight drugs,
·         Stability and absorption of proteins that normally cannot be taken orally,
·         Extend the life cycle of existing drug formulation.

At present many substances are under investigation for drug delivery and more specifically for cancer therapy, AIDS and potential to cross the Blood Brain Barrier (BBB) has open new ways for drug delivery into the brain. Pharmaceutical sciences are also using nanoparticles to reduce toxicity and side effects of drugs. Nanoparticles are also have the potential as novel intravascular or cellular probes for both diagnostic and therapeutic purposes (drug/gene delivery) and nanosize allow access into cell and cell compartment including nucleus. . Discovery of nanomedicine has given rise to nanoparticles through which better target specific drug and gene delivery is possible. In conclusion nanoparticles for drug delivery and imaging have gradually been developed as new modalities for cancer therapy and diagnosis. This review illustrates the emerging role of nanotechnology in drug delivery.

ESKAG, A 100 Crores Group with its presence in pharmaceutical, health care & bulk drugs having manufacturing units at west bengal and uttarakhand, now in hormonal therapy with its speciality division - REWEL invites applications to work in districts of West Bengal and Kolkata city.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer.

About Authors:
Singh Asheesh^1*, Bajpai Dinesh¹, Singour P.K.^2
1Centre for Research & Development, Ipca Laboratories Ltd; Sejavta; Ratlam (MP) - 457002
²Faculty of pharmacy VNS Institute, Neelbud Bhopal (MP) - 462042
*asheesh_parihar@yahoo.com

Abstract:
Stevia rebaudiana is a well known medicinal herb contains antibacterial, antifungal, anti-inflammatory, anti-viral, anti-yeast, cardiotonic diuretic and hypoglycaemic properties. This herb has been used in Ayurveda in India since centuries. Stevia is a perennial herb belonging to the family Asteraceae, is one of the most valuable tropical medicinal plant. All over world there is increasing tendency towards consuming natural products and thus living a natural life and. At the same time our life styles have changed so much over the last 4-5 decades that sweeteners (either high calorie natural or proceeded sugars or high potency and low calorie sweeteners such as Aspartame) have become integral part of our natural daily diet. Stevia is a new crop in that is gaining very high popularity amongst all type of sweetener users as most ideal substitute for sugar. Sugar is basically a chemical that has grown in market over last many years. But in this age of changing life styles and people becoming more conscious of their health, the worldwide sugar consumption is going down and is getting replaced by low calorie sweeteners. Many of these Sweeteners are complex chemicals or many times naturals as well.

About Author:
Sandeep Kaur
M.Sc. Microbiology (Hons.) in 2012
Guru Nanak Dev University, Amritsar,
Punjab- 143001.
sandy.flowers305@gmail.com

ABSTRACT:
Medicinal plants are part and parcel of human society to combat diseases from the dawn of civilization. India is sitting on a gold mine of well-recorded and traditionally well practiced knowledge of herbal medicine. India officially recognizes over 3000 plants for their medicinal value and Terminalia plant (Baheda) is one of them. Terminalia species (Family: combretaceace) including Terminalia bellerica, Terminalia arjuna and Terminalia chebula are widely used medicinal plants throughout India and popular in various Indigenous system of medicine like Ayurveda, Sidda and Unani. Terminalia chebula, is called ‘King of Medicine’ in Tibet, because of its extraordinary power of healing. Terminalia plant has been demonstated to possess multiple pharmacological and medicinal activities, such as antioxidant, antimicrobial, antidiabetic, anti-inflammatory, anticancer & tumor and wound healing activity. In the Indian Sytem of Medicine, whole plant including stem bark, fruit, root bark and seeds are used as astringent, cooling, aphrodisiac, cardiotonic, tonic in fractures, ulcers, spermatorrhoea, leucorrhoea, cough, excessive perspiration and skin disorders. Phytoconstituents such as glucoside, tannins, gallic acid, ellagic acid, ethylgalate, gallylglucose and chebulanic acid are mainly believed to be responsible for its wide therapeutic actions. The present review is therefore, an effort to give a detailed survey of the literature on pharmacognosy, phytochemistry and pharamacological activities of the plant1.