January 2012

Clinical Development Services Agency (CDSA) is an extramural unit of Translational Health Science and Technology Institute (THSTI) and has been established as a not-for-profit society to provide cost affective, high quality preclinical and clinical product development support services to meet the country’s growing healthcare needs. It will tend enterprises; particularly SMEs involved in new technology innovation and facilitate translation of scientific know-how into viable products.

Applications are invited for the position of Junior Research Fellow (JRF) in Department of Biotechnology (DBT) sponsored project “Targeting the mitochondria dependent and independent apoptotic signaling by Nanoparticulate drug conjugate to induce apoptosis in cancer cells”.

National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). It is situated in the vicinity of a number of hospitals and research institutes in central Mumbai.

Rajendra Memorial Research Institute of Medical Sciences, Patna, a permanent Institute under Indian Council of Medical Research, Dept. of Health Research, Ministry of Health & Family Welfare, Govt. of India, invites applications from suitable Indian Nationals for appointment on the following posts:

The Regional Centre of Institute of Bioresources and Sustainable Development (RCIBSD) is established under the aegis of Department of Biotechnology, Government of India in order to utilize the rich bioresources including plants, animals and microbial resources of the Sikkim Himalayas through scientific interventions for economic benefit of the region.

About Authors:
RESHMY RAJAN
DEPT OF PHARMACEUTICS, AMRITA SCHOOL OF PHARMACY,
AIMS HEALTH CARE CAMPUS,
KOCHI 682041

ABSTRACT
Dental diseases are recognized as a major public health problem, in civilized society. The prevalence of tooth decay, various dental diseases, and tooth loss are so great that a permanent healthy oral system in the body is almost impossible. Dental diseases are studied by oral examination of a particular section of the population and the incidence measured by the number of new cases occurring in a given period of time. In UK it is estimated that 99% of children under 12 years suffer from dental caries.  Modern dentifrices compositions contain numerous components that have various therapeutic and cosmetic functions. Fluoride was the first of the therapeutic additions to the basic dentifrice formulations. Most of the dental compositions contain an abrasive cleansing agent which aids in the removal of adherent deposits on the teeth. Advertising and taste rather than therapeutic superiority determine the market advantage. During the past decade, however, it has not been enough for a dentifrice to prevent tooth decay or create a smile that will win the man, woman or job of one's dreams. Now, it seems, a dentifrice must fight tartar, plaque and gum disease as well. And manufacturers do not want to forget "niche" consumers -smokers, natural product fans, people with tooth sensitivity, and those with dry mouths. Sustained-release delivery systems allocate extended drug action to treat dental and periodontal diseases compared to the conventional dosage forms. Herbal extracts have been successfully used in dentistry as tooth cleaning and antimicrobial plaque agents. Only two out of ten 5-year old have sound teeth according to the General Dental Council.The present review deals with the various novel formulations of dentifrices.

J. B. Chemicals & Pharmaceuticals Ltd. (JBCPL), known to many as Unique Pharmaceutical Laboratories is one of India's leading global pharmaceutical companies. The company manufactures and markets a wide range of pharmaceutical formulations.

Post:  Officer/Executive - Corporate Quality Assurance

Flamingo Pharmaceuticals Ltd. is a quality driven pharmaceutical company with an experience of over two decades in global markets, exporting to 52 countries and having Rs.200 crores+ turnover. Flamingo has WHO-GMP/UK MHRA certified 100% EOU unit.