Monthly archive | PharmaTutor

11 November 2011

Vacancy in United Biotech for the post of DRA Executive

United Biotech has been a trend setter of new standards and is among the fastest growing companies in the Indian pharmaceutical Industry. In a span of 12 years it has established an enviable reputation and track record for adopting latest manufacturing technologies, introducing world-class quality of products, ground breaking Research & Development efforts in association with its foreign counterparts and for setting new standards of customer service.

11 November 2011

METHOD DEVELOPMENT AND ITS VALIDATION FOR ESTIMATION OF TORSEMIDE IN TABLET DOSAGE FORM

About Authors:
Kapil Sharma¹*, Subhash Gupta ², Yogesh Sharma¹
1 Yaresun Pharmaceuticals Pvt. Ltd.Jaipur - 302006, Rajasthan, India.
2 Oasis test house ltd.jaipur-302006,
Rajasthan, India.

METHOD DEVELOPMENT AND ITS VALIDATION FOR ESTIMATION OF TORSEMIDE IN TABLET DOSAGE FORM BY RP-HPLC AND UV SPECTROPHOTOMETRY AND COMPARISON OF TWO DEVELOPED METHODS BY USING t-TEST

ABSTRACT
One HPLC and one UV spectrophotometric method have been developed for the determination of torsemide (TRS) in tablet dosage form. The first method is based on determinetion of TRS in tablet dosage form by RP- HPLC method. Chromatgraphy was carried out on a nucleosil C-18,250 x 4.6 mm column using a mixture of phosphate buffer and methanol (50:50 v/v) as the mobile phase at a flow rate of 1.3 ml/min. Run time was 15 min. Detection was done at 288 nm and retention time of the drug was 7.05 min. This method produced linear responses in the concentration range 60-140 µg/ml of torsemide. The accuracy of the method was assessed by recovery studies and was found to be 99.90± 0.41 for torsemide. The second method is based on the estimation of torsemide in tablet dosage form by UV spectrophotometry using 50% v/v methanol in distilled water. Beer’s law obeyed over the concentration range 2-26 µg/ml at 288 nm with apparent molar absorptivity of 1.26 x 10⁴. Both developed methods were found to be applicable for routine analysis of drug in tablet dosage form. The result of the analysis were validated statistically.The results were compared obtained from UV spectrophotometry and HPLC.

11 November 2011

Microsphere: An Overview

About Author:
Rajesh Mujoriya
Sardar patel college of technology,
Balaghat, dis. Balaghat,
MP–481001,INDIA

Abstract
Microspheres offer an excellent solution to creating precise pore sizes in ceramics at reasonable prices. Polyethylene microspheres offer the added benefit of minimal residue after firing, and the availability in wide size ranges from a few micron up to 1000um (1mm). Highly spherical microspheres have the added benefit of creating strong pores without any stress risers. Biodegradable microspheres are used to control drug release rates thereby decreasing toxic side effects, and eliminating the inconvenience of repeated injections. Microparticulate carrier system can be administered through different routes such as i.v,ocular,i.m,oral,intra arterial.etc.Each routes has it’s own biological significance, limitation & pharmaceutical feasibility.

10 November 2011

Openings for Project Fellow and Lab attendent in Department of Pharmacy @ Banaras Hindu University

Banaras Hindu University ranks among the first few in the country in the field of academic and research output. This university has two campuses, 3 institutes, 16 faculties, 140 departments, 4 advanced centers and 4 interdisciplinary schools.

10 November 2011

Fresh Pharma Graduates invited to work as Product Specialist in Biocon

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.

10 November 2011

Work as Manager / Senior Manager, Production in Pfizer

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support.

10 November 2011

Submit applications for Research Associate(RA-1, RA-2, RA-3) in National Brain Research Centre

The National Brain Research Centre (NBRC) was established by the Department of Biotechnology, Ministry of Science & Technolgy, Government of India, in November 1997 as a fully funded autonomous research institute in the area of neuroscience and brain. The Centre was registered as an Society in June 1999 under the Registration of Societies Act.

10 November 2011

Vacancies in Nirma University for Para Medical Staff

Functioning under the aegis of Nirma Education and Research Foundation (established in 1994), the university presently includes of a top grade – Institute of Technology (1995), a leading b-school – Institute of Management (1996), an innovative Institute of Diploma Studies (1997), an upcoming Institute of Pharmacy (2003), Institute of Science (2004) and emerging Institute of Law (2007). All these institutions have emerged as centers of excellence offering various programmes ranging from undergraduate to doctoral le

10 November 2011

Walk in for the post of Senior Project Fellow at INSTITUTE OF HIMALAYAN BIORESOURCE TECHNOLOGY

Govt. of Himachal Pradesh took up initiative in early seventies to set up a CSIR lab to make prudential use of the natural resources of the region. After several levels of discussions a formal request was made by then Chief Minister of HP to Vice President, CSIR in 1982 for initiating the matter, and giving final shape to the proposal.