November 2011

Anglo French Drugs & Industries is a dynamic, rapidly expanding pharmaceutical company with established capabilities in the development of therapeutic formulations, marketing & sales, distribution and contract manufacturing.

J.B. Chemicals & Pharmaceuticals Ltd. is a fast growing Indian Pharmaceutical Company with a turnover of more than 850 crores. The company has excellent products like Nicardia, Metrogyl and Rantac. The company intends to expand its domestic presence by mass expansions in Mumbai for its Unique Division (Main Division).

Meyer, an associate of London based multinational Vitabiotics Ltd.,is a rapidly growing Pharma Co. in India. Leading pharmaceutical manufacturer, founded in 1982 .,in technical collaboration with OMEGA-MEYER Ltd Jersey( Br. Isles). H.O. based in THANE

Post: MANAGEMENT TRAINEE – REGULATORY AFFAIRS

About Authors:
Hardwari L. Yadav, P.K. Singour, R.S. Pawar, U. K. Patil
Department of Pharmaceutical Chemistry,
VNS Institute of Pharmacy,
Neelbud, Bhopal (M.P.)

Abstract
Chalcone are the important constituent of many natural sources and have variety of biological activities. The novel chalcone derivatives isolated from the fruits of Mallotus philippinensis called mallotophilippens. The chalcones are synthesize by claisen-schmidt base catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehyde or substituted benzaldehydes. Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. Recent reports suggest antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.

About Author: Ashish Kumar Verma¹, D.Raj. Anand¹, Garima A. Tewari²
1.    Jubilant Chemsys Limited Noida 201301
2.    Babu Banarsi Das University Lucknow

ABSTRACT
Aceclofenac and paracetamol in combination are available as tablet dosage forms in the ratio of 1:5. A simple, reproducible and efficient method for the simultaneous determination of aceclofenac and paracetamol in synthetic mixture was developed. The proposed method is based on the Q-analysis UV Spectrophotometric method. The absorbance maxima of aceclofenac and paracetamol were found to be 275.4 nm and 248 nm, respectively in methanol. In Q-analysis, the isoabsorptive point for both the drugs was found at 266.1 nm. The linearity range lies between 1-35 µg/ml for aceclofenac and 1-15 µg/ml for paracetamol at their respective wavelengths. Both the drugs obey Beer’s law. The recovery studies confirmed the accuracy of the proposed methods.

Lupin Pharmaceuticals, Inc. is the U.S. wholly owned subsidiary of Lupin Limited, which is among the top six pharmaceutical companies in India. Through our sales and marketing headquarters in Baltimore, MD, Lupin Pharmaceuticals, Inc. is dedicated to delivering high-quality, branded and generic medications trusted by healthcare professionals and patients across geographies.

ANSWERS of Previous PharmaQUIZ-4:
1.B   2.B   3.A   4.A   5.C
6.D   7.A   8.C   9.C   10.A
SEE QUESTIONS OF QUIZ - 4