July 2011

The history of Jamia Hamdard begins with the establishment of a small Unani clinic in the year 1906 by Hakeem Hafiz Abdul Majeed, one of the well-known practitioners of Unani System of Medicine of his time. Hakeem Hafiz Abdul Majeed had a vision of making the practice of Unani Medicine into a scientific discipline so that Unani medicines could be dispensed in a more efficacious manner to patients. He gave the name "Hamdard" to his venture which means "sympathy for all and sharing of pain".

Manav Group of Institutes is one of the leading educational group with Manav Institute Mof Technology & Management (Woman), Manav Institute of Education, Manav Institute of Pharmacy under its umbrella. Manav Nirman Samiti is the visionary body and the source of inspiration.

The Indian Institute of Toxicology Research (IITR), established in 1965, a constituent laboratory of Council of Scientific & Industrial Research (CSIR) engaged in the Research & Development in the areas of Environmental Toxicology, Predictive Toxicology, Health Risk Assessment, Preventive Toxicology, Inhalation Toxicology, Analytical Toxicology, and also National S&T Missions. IITR has two campuses; the main campus is located at the centre of Lucknow City and the other campus at a distance of approx.

About Authors: Ashwini K. Reddy, Swetha, Gauthami, Srivally, Masoom - M.Pharm, Helen Sheeba - Assistant Professor. Malla Reddy Institute of Pharmaceutical Sciences, Hyderabad.

Reference ID: PHARMATUTOR-ART-1076

HIGH - THROUGHPUT screening (HTS) is an approach to drug discovery that has gained widespread popularity over the last three or four years. HTS is the process of assaying a large number of potential effectors of biological activity against targets (a biological event). The methods of HTS are applied to the screening of combinatorial chemistry, genomics, protein, and peptide libraries. The goal of HTS is to accelerate drug discovery by screening large libraries often composed of hundreds of thousands of compounds (drug candidates) at a rate that may exceed 20,000 compounds per week. This paper will focus on assay adaptations, robotic equipment, and implementation strategies that allow HTS programs to be successful. Ultrahigh throughput screening (UHTS) issues (testing of 100,000 compounds / day) will also be discussed.

About Authors: Rekha. S^1*
1*Department of Pharmacology, Mother Theresa Postgraduate and Research Institute of Health Sciences, Indira Nagar, Gorimedu, Puducherry 605 006.
Kavimani. S^1
1Professor and Head, Department of Pharmacology, Mother Theresa Postgraduate and Research Institute of Health Sciences, Puducherry.

Reference ID: PHARMATUTOR-ART-1069

Summary
Objective
The present study was undertaken to further evaluate the adverse effect potential of Prulifloxacin to induce arthropathy in rats with reference to its duration of treatment.

Methods
Groups of one month old young rats were administered Prulifloxacin intraperitonially 200 mg/kg and 400 mg/kg doses for 15 and 30 days respectively. Control group received normal saline. At the end of treatment
period, animals in each group were subjected to serum alkaline phosphatase estimation. The serum alkaline phosphatase assay was carried out by using alkaline phosphatase reagent kit.