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14 May 2011

AN OVERVIEW ON INTELLECTUAL PROPERTY RIGHTS IN PHARMACEUTICAL PATENT

About Author: A. A. Durgavale*, M. V. Mahale, S. R. Kane, Dr. S. K. Mohite, Dr. C. S. Magdum
Department of Quality Assurance,
Rajarambapu College Of Pharmacy,
Kasegaon, Tal - Walwa, Dist. - Sangli - 415404

Reference ID: PHARMATUTOR-ART-1058

Abstract
Intellectual Property (IP) refers to property created with the use of intellect. In other words, this refers to creation of mind. These are rights given to person over creation of their minds. They usually give the creator an exclusive right over use of his or her relation for certain period of time. Intellectual property differs from other form of properties as it does not have any physical shape and can be seen. Protection of Intellectual property is done by offering time limited rights to investor in form of patents.
Intellectual property laws vary from jurisdiction to jurisdiction, such that the acquisition, registration or enforcement of IP rights must be pursued or obtained separately in each territory of interest. However, these laws are becoming increasingly harmonized through the effects of international treaties such as the 1994 World Trade Organization (WTO) Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPs), while other treaties may facilitate registration in more than one jurisdiction at a time. Certain forms of IP rights do not require registration in order to be enforced. There are various forms of IP like Copyrights and related rights, Trade Marks, Geographical Indications, Industrial Designs, Lay out Designs of Integrated Circuits, Protection of Undisclosed Information (Trade Secrets), Patents, Plant varieties.

14 May 2011

An Emerging Complication of P. Vivax Malaria with Comparison of P. Falciparum Malaria

About Author: Dr.Ravindra Kembhavi, Asso. Professor PSM Department,
KEM hospital, Parel, Mumbai
Dr.Mahesh Ghadage, M.Sc pharmaceutical 2^nd year student,
KEM hospital, Parel, Mumbai

Reference ID: PHARMATUTOR-ART-1057

Abstract
Severe or complicated P. vivax malaria seldom results in pulmonary damage, and pulmonary complications are exceedingly rare while acute renal failure, disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), hypoglycemia, coma, or epileptic seizures this are manifestations of severe or complicated P. falciparum malaria.

14 May 2011

Development and Validation of New Analytical Method for Estimation of Drotaverine in Bulk and Pharmaceutical Dosage Form by UV Spectrophotometry

About Author: Khuntia Bhabani S., M.Pharm., B.P.U.T.,
Department of Pharmaceutical Analysis and Quality assurance,
Royal College of Pharmacy and Health Sciences,
Berhampur, Odisha, India

Reference ID: PHARMATUTOR-ART-1056

Abstract
The present study includes a simple, sensitive and specific UV method development and validation for the quantitation of Drotaverine in bulk and pharmaceutical dosage form. The λmax was found to be 357nm by taking acetonitrile and water (50:50) as solvent. The validation of the proposed method was carried out as per ICH Guidelines. It was found that the drug was shown the linearity between the range 5-90µg/ml. The regression of the curve was y = 0.022x - 0.033. The developed method was found to be with %RSD 0.548499 for Drotaverine. The %RSD for intra-day and inter-day precision was lower than 2%. The percentage recovery values of pure drug from the reanalyzed solution of formulation were in between 95.68-99.5%. The ruggedness of the method was studied by taking in account of different analyst and by varying the temperature. Based on the performance characteristic the proposed UV method was found to suitable for the estimation of Drotaverine in bulk and pharmaceutical dosage form.

13 May 2011

FORMULATION AND EVALUATION OF FLOATING MICROSPHERES OF METFORMIN HYDROCHLORIDE

About Author: Rajyalakshmi Dhulipati (B.Pharm), Janardhanreddy Ramareddy P. (M.Pharm), G. Rajalakshmi (M.Pharm, Lecturer), Dr. N. Damodharan (M.Pharm, Ph.D, Professor & Head of the Department)
Department of Pharmaceutics,
SRM College of Pharmacy, SRM University,
Kattankulathur-603203, Kancheepuram Dist., Tamil Nadu.

Reference ID: PHARMATUTOR-ART-1055

Abstract
The main aim of the study is to formulate and evaluate floating microspheres of Metformin Hydrochloride. Gastro retentive floating microspheres have emerged as an efficient means of enhancing the bioavailability and controlled delivery of many drugs. Floating microspheres of microspheres are formulated in order to achieve an extended retention time in upper G.I.T. which results in enhanced absorption and thereby improving the bioavailability. Floating microspheres were prepared by Non aqueous solvent evaporation method by using Eudragit RS 100 and Eudragit RL 100. The pure drug, the polymers and the physical mixtures were evaluated for FTIR. The prepared Metformin hydrochloride microspheres were evaluated for surface topography, angle of repose, bulk density, tapped density, carr’s index, hausner’s ratio, yield of microspheres, particle size analysis, drug entrapment efficiency, invitro floating ability, invitro drug release and kinetic studies. Results showed that there were no drug incompatibilities and there was good floating ability. SEM revealed the size and surface morphology. The Preformulation parameters were found to be satisfactory. Drug entrapment efficiency was found to be 70-135% and yield was found to be 70-95%. The drug release profiles showed that microspheres prepared with Eudragit RS 100 showed less release when compared to Eudragit RL 100. When Eudragit RL 100 was used in combination with Eudragit RS 100, the release was found to be faster when compared to Eudragit RS 100 alone. The release data obtained were fitted to Higuchi and Korsemeyer-Peppas model to indicate that the mechanism of the drug release was non fickian type of diffusion.

13 May 2011

Job as a Franchise Team Lead, Medical Communciations @ Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

13 May 2011

Require Group Head, Medical Communications @ Novartis

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

13 May 2011

Opening for QC Executive at Anglo French Drugs & Industries Ltd.

Anglo French Drugs & Industries is a dynamic, rapidly expanding pharmaceutical company with established capabilities in the development of therapeutic formulations, marketing & sales, distribution and contract manufacturing.

13 May 2011

Job as a Material Management Executive/Manager - Supply Chain @ Virchow Laboratories Ltd. - 2 Openings

13 May 2011

Work as a Regional Business Manager in Tablets India Ltd.

Tablets India Limited (TIL) is one of the leading manufacturers of various types of Pharmaceutical and nutraceutical formulations. The vital therapeutic range includes nutritional supplements, haematinics, hepatoprotectives, novel antipyretic, a unique G.I. Lavage preparation, Anti-Ulcerant, Osteoporotic Formula, Respiratory Medicine, etc.

12 May 2011

Walk in @ Indian Institute of Integrative Medicine : Require Research Associate

Indian Institute of Integrative Medicine a constitutional establishment of the of the Council of Scientific and Industrial Research, wishes to recruit Research Associate(s) on temporary basis to work in various sponsored project in the Institute and to make a panel of the selected candidates for future project positions.

Post: RESEARCH ASSOCIATE

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May 2011

AN OVERVIEW ON INTELLECTUAL PROPERTY RIGHTS IN PHARMACEUTICAL PATENT

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