April 2011

About Authors:  RAJESH Z. MUJORIYA,
M.PHARM.(PHARMACEUTICS)
Assistant Professor,
sardar patel college of technology, balaghat M.P.

ABSTRACT
Pantoprazole sodium is proton pump inhibitor and used as an antiulcer agent.  The study was undertaken with an aim to formulate pantoprazole sodium enteric coated pellets.
Before going to develop the formulation a detail product literature review was carried out to know about the MUPS and type of dosage form available in market. The present study was focused to formulate delayed release capsule by MUPS Technique.
Average pellets size was determined by sieve analysis and found to be 1680-1200 microns (ASTM sieve no. 12-16). Sieve analysis was the essential step before coating. Because uniform sized pellets undergo effective coating. The result indicates a effective enteric coating and delay the drug release, with 32% acryl ezee solution, is possible. The formulation developed can further be worked on. For identifying a best formulation for delayed release pellets of pantoprazole sodium.

The University of Kashmir is spread over 263 acres of lush green land with three adjacent campuses of exquisite beauty, Amar Singh Bagh, Naseem Bagh and Mirza Bagh. Amar Singh Bagh is located on the bank of the Dal having on its other three sides a background of mountainous amphitheatre rising to a great height above its crystal clear water.

Swami Vivekanand Subharti University is a University under section 2(f) of the University Grant Commission (U.G.C.) Act, 1956 having been setup under the Swami Vivekanand Subharti Vishwavidhaylaya Uttar Pradesh Adhiniyam,2008(U.P.Act No.29 of 2008)as passed by Uttar Pradesh legislature and and assented by the Hon'ble Governer Of Uttar Pradesh in September 2008.

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