Rajasthan

Mohanlal Sukhadia University (erstwhile Udaipur University) at Udaipur is a State University established by an Act in the year 1962 to cater the needs of higher education in Southern Rajasthan. The University is located in Aravalli Hill Area largely dominated by tribal populations. Endowed with rich cultural heritage, natural resources and beautiful landscape, Udaipur is a world renowned tourist attraction.

On-line applications are invited for appointment of teaching faculties on regular basis for the following posts:

Post: Assistant Professor

National Health Mission (NHM), Rajasthan State Health Society, invites applications for various positions of Managers/Consultants/Ofificers/Coordinators and Assistants at State HQ on contractual basis under National Rural Health Mission (NRHM) Rajasthan.

The details of various positions, required essential qualifications & experience, maximum age limit etc.are as under:

Post: Logistic Manager, Consultant

FCI Aravali Gypsum & Minerals India Limited (FAGMIL) is Government of India undertaking under the Ministry of Chemical & Fertilizers. FAGMIL was earlier a part of Fertilizer Corporation of India Ltd., functioning as Jodhpur Mining Organization. It is engaged in Mining & exploration of mineral Gypsum.

Post: Jr. Chemist

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ABOUT AUTHORS:
Amarjeet Singh*, Sudeep Bhardwaj, Ashutosh Aggarwal
Department of Pharmacology,
Seth G. L. Bihani S. D. College of Technical Education,
Institute of Pharmaceutical Sciences & Drug Research,
Sri Ganganagar, Rajasthan 335001, India
*amarjeetsingh024@gmail.com

ABSTRACT
Objective: The choice of drug for the treatment of hypertension changes at short intervals. Drug utilization studiesconducted at regular intervals help to guide the physician in prescribing drugs rationally. The present study was done toanalyze the prescribing patterns of antihypertensive drugs in a NorthIndian  hospital.

Material & method: A retrospective, crosssectional analysis of prescriptions of antihypertensive cases admitted in Medicine in-patient wards of civil hospital of Sri Ganganagar was conducted. All the prescription files with diagnosis ofessential hypertension were analyzed. Prescriptions for hypertension with other co-morbid conditions were also included. Frequency and proportions of utilization of antihypertensive medications were charted and figured.

Result: During the studyperiod, there were 435 prescriptions for essential hypertension. The most frequently prescribed antihypertensive medications were:  monotherapy (42.06%), (57.94%) of patients were on multiple drugtherapy, the most favored fixed drug combination being diuretics with angiotensin receptor blockers (31.74%).

Conclusion: The present study revealed that Angiotensin receptor blockers arethe drugs of choice as monotherapy and as combination therapy for hypertensives. This pattern of prescription is also supported by the current JNC VIII guidelines for the treatment of hypertension.

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ABOUT AUTHORS
Amarjeet Singh*, Sudeep bhardwaj, Ashutosh aggarwal
Department of Pharmacology,
Seth G. L. Bihani S. D. College of Technical Education,
Institute of Pharmaceutical Sciences & Drug Research
amarjeetsingh024@gmail.com

ABSTRACT
Objective: The purpose of this study was to examine the risk assessment of developing type 2 diabetes mellitus in patient on antihypertensive medication.

Material & Method: In the present study total 30 patient with essential hypertension of both sex with mean age (48.6±0.8313) were recruited as per the inclusion criteria. Patients were segregated on the behalf of therapy they were using. 22 patients were on Losartan+HCTZ therapy and 8 patients were on Atenolol therapy.

Result: After six month of antihypertensive therapy Atenolol group showing a significant difference in their blood glucose (0.0014) whereas in Losartan+HCTZ group significant difference was not observed (0.1542). Patients of Atenolol group when compared with patient of Losartan+HCTZ group a significant difference was observed in the serum cholesterol level (0.0290).

Conclusion: We found that the use of β-blocker was independently associated with increased risk of type 2 diabetes. So increase in blood glucose in the Atenolol group patient revealed a significant association between use of Atenolol therapy and metabolic dysfunction whereas in Losartan+HCTZ group significant increase in blood glucose was not observed and from these we can conclude therapy with Losartan+HCTZ therapy not associated with metabolic dysfunction.

A Walk in Interview will be held at the O/o the Chief Medical Officer, Gomati Tripura, Udaipur as per scheduled date and time as mentioned below for filling up the following posts at Gomati district on purely contractual basis at a fixed pay as shown against each under District Health & Family Welfare Society, NHM, Gomati Tripura in connection with formation of "Dedicated School Health Team" under RBSK (Rastriya Bal Swasthya Karakram) and functioning of Mobile Medical Unit.

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ABOUT AUHTORS:
Suresh Rewar¹*, Bansal BK¹, Singh CJ², Sharma AK^2
1Department of pharmaceutics, Arya College of Pharmacy, Jaipur, Rajasthan India
²Department Of Pharmacology, Arya College of Pharmacy, Jaipur, Rajasthan India
sureshrewar1990@gmail.com

ABSTRACT
Chronopharmaceutical drug delivery systems are gaining a lot of interest as they deliver the drug at the right site of action, right time and right amount, as per the pathophysiological needs of the diseases. These systems are basically time-controlled drug delivery systems in which the system controls the lag time independent of environmental factors like pH, enzymes, GIT motility, etc. These systems are designed for chronopharmacotherapy which is based on the circadian rhythm of the body. The effectiveness and toxicity of many drugs vary depending on dosing time associated with 24 hr. rhythms of biochemical, physiological and behavioral processes under the control of circadian clock. The chronobiology of the various common 24-hour BP profiles seen in hypertensive patients in relation to cardiovascular risk and end-organ injury and ultimately the control and normalization of abnormal BP throughout daytime activity and night time sleep. Chronopharmacotherapy provides a means of individualizing the treatment of hypertension according to the circadian BP profile of each patient, and constitutes a new option to optimize BP control and to reduce the risk of cardiovascular disease. Various latest and upcoming marketed technologies of Chronopharmaceutical drug delivery used in treatment of hypertension diseases like OROS^®, CODAS^®, CEFORM^®, DIFFUCAPS^®, PULSINCAP^® etc.