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  • The drug fasudil is found to reverse key symptoms of schizophrenia in mice

    A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment. Their findings, which were published in Pharmacological Research, suggest new therapeutic approaches for treating schizophrenia patients.

  • NIH RECOVER research identifies potential long COVID disparities

    Black and Hispanic Americans appear to experience more symptoms and health problems related to long COVID(link is external), a lay term that captures an array of symptoms and health problems, than white people, but are not as likely to be diagnosed with the condition, according to new research funded by the National Institutes of Health.

  • Toxic protein linked to muscular dystrophy and arhinia

    Researchers at the National Institutes of Health and their colleagues have found that a toxic protein made by the body called DUX4 may be the cause of two very different rare genetic disorders. For patients who have facioscapulohumeral muscular dystrophy (FSHD), or a rare facial malformation called arhinia, this research discovery may eventually lead to therapies that can help people with these rare diseases.

  • Oral bacteria may increase heart disease risk

    Infection with a bacterium that causes gum disease and bad breath may increase the risk of heart disease, shows a study published today in eLife.

    The study suggests another potential risk factor that physicians might screen for to identify individuals at risk of heart disease. It may also indicate that treatments for colonisation or infection with the oral bacterium Fusobacterium nucleatum may help reduce heart disease risk.

  • Rice scientists reengineer cancer drugs to be more versatile

    Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated. lab shotRice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

  • The new prostate cancer blood test with 94 per cent accuracy

    Researchers at the University of East Anglia have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods.

    New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 per cent accurate – beating the currently used prostate-specific antigen (PSA) blood test.

    The research team say that the new test shows significant potential as an accurate and rapid cancer screening diagnostic.

  • Possible underlying cause of dementia detected

    A new Cedars-Sinai study suggests that some patients diagnosed with behavioral-variant frontotemporal dementia (bvFTD)—an incurable condition that robs patients of the ability to control their behavior and cope with daily living—may instead have a cerebrospinal fluid leak, which is often treatable.

    Researchers say these findings, published in the peer-reviewed journal Alzheimer’s & Dementia: Translational Research and Clinical Interventions, may point the way to a cure.

  • Mimicking an Enigmatic Property of Circadian Rhythms through an Artificial Chemical Clock

    An innovative temperature-compensation mechanism for oscillating chemical reactions based on temperature-responsive gels has been recently reported by researchers at Tokyo Tech. Their experimental findings, alongside a detailed mathematical analysis, hint at the possibility that circadian rhythms found in nature may all rely on a similar mechanism, allowing their period to remain independent of temperature.

  • Hypertension drug could be repurposed to delay ageing : study finds

    Researchers have found that the drug rilmenidine can extend lifespan and slow ageing.

    Published in Aging Cell, the findings show that animals treated with rilmenidine, currently used to treat hypertension, at young and older ages increases lifespan and improves health markers, mimicking the effects of caloric restriction.

  • Targeted test for antibiotic resistance in clinical Enterobacter species

    Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used antibiotics, so that the reserve antibiotic colistin is increasingly used as a last resort therapy option. To avoid unnecessary reliance on colistin and risk increasing resistance, bacteria are tested for sensitivity or resistance to colistin before recommending treatment. However, commonly used tests for Enterobacter are not reliable.

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