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  • Breakthrough research makes cancer-fighting viral agent more effective

    Researchers from Aarhus University have made a significant breakthrough by discovering that the drug 4-OI can enhance the effectiveness of a cancer-fighting viral agent. This may lead to treatment of cancers that are otherwise resistant to therapies.
  • Study reveals why AI models that analyze medical images can be biased
    Artificial intelligence models often play a role in medical diagnoses, especially when it comes to analyzing images such as X-rays. However, studies have found that these models don’t always perform well across all demographic groups, usually faring worse on women and people of color.
  • New Approach Accurately Identifies Medications Most Toxic to the Liver
    The current method for assessing medication-related liver injury is not providing an accurate picture of some medications toxicity or lack thereof to the liver, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Classification of a medication’s potential to damage the liver, termed hepatotoxicity, has been historically determined by counting individual reported cases of acute liver injury
  • New study demonstrates the efficacy of a promising celiac disease drug at the molecular level

    A recent study led by researchers at Tampere University investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease. Previous tissue studies have shown that the ZED1227 transglutaminase 2 inhibitor prevents gluten-induced intestinal damage. The results of the new study, based on an analysis of the molecular activity of more than 10,000 genes, provide very strong evidence that the first successful drug to treat celiac disease may be at hand.

  • New and crucial role discovered for a protein in the body's immunity against cancer

    Researchers at the University of Turku in Finland have found a new function for an existing protein. They discovered that TIMP-1, a protein traditionally known to prevent damage to the body's cells and tissues, plays a critical role in the immune system's defence against cancer. The findings of the study could improve the effectiveness of current cancer immunotherapies.

  • Risk of death from COVID-19 lessens, but infection still can cause issues 3 years later

    New findings on long COVID long-term effects on health experienced by many who have had COVID-19 present a good-news, bad-news situation, according to a study at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

  • Researchers take step toward development of universal COVID-19 antibodies

    SARS-CoV-2, the virus that causes COVID-19 disease, continues to evolve and evade current vaccine and therapeutic interventions. A consortium of scientists at Texas Biomedical Research Institute (Texas Biomed), the University of Alabama at Birmingham (UAB) and Columbia University have developed a promising new human monoclonal antibody that appears a step closer to a universal antibody cocktail that works against all strains of SARS-CoV-2.

  • Antioxidant gel preserves islet function after pancreas removal
    Before surgeons remove the pancreas from patients with severe, painful chronic pancreatitis, they first harvest insulin-producing tissue clusters, called islets, and transplant them into the vasculature of the liver. The goal of the transplant is to preserve a patient’s ability to control their own blood-glucose levels without insulin injections.
  • Google wants to index your DNA
    A new DNA search tool, akin to a Google for genetic material, shows great potential, as reported by its Swiss creators. In a groundbreaking study, they managed to index 10 percent of the globes known DNA, RNA, and protein sequences, suggesting that this approach could feasibly expand to encompass the entirety of biological sequence data.
  • Rare Disease DNA-Damaging Mutation could have consequences for more common conditions
    TREX1 is a gene that is supposed to direct the maintenance of the entire body DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy
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