• PharmaTutor
    23 July 2013

    WAFERS TECHNOLOGY – A NEWER APPROACH TO SMART DRUG DELIVERY SYSTEM

    ABOUT AUTHORS:
    Papola Vibhooti *, Dr. Kothiyal Preeti
    Shri Guru Ram Rai Institute of Technology & Sciences
    Dehradun, Uttarakhand, India
    *papola.vibhooti47@gmail.com

    ABSTRACTS
    The lyophilized wafer developed throughout this review is an effective and versatile drug delivery system for oramucosal application. This has been established from the extensive physicochemical and physic mechanical profiling conducted. Through a screening and selection of polymers, HPC had the lowest gelation characteristics and was therefore suitable for the development of the wafer system. Suitable excipient and polymer combinations were established which allowed for the development of rapidly disintegrating and prolonged release wafer systems. The wafer system containing HPC, lactose, mannitol and glycine had the ability to disintegrate within 30 seconds. The modified wafer system, consisting of pectin cross linked with zinc ions serving as the drug reservoir, and mucoadhesive polymer combination of pectin, carmellose and gelatin, provided effective release of model drug diphenhydramine hydrochloride over approximately six hours. The modification of this technology to provide a prolonged release mucoadhesive system seems promising. It is envisaged that this system will be applicable to many drugs requiring the extended release of bioactive material. Therefore, the lyophilized wafer matrices developed in this study are highly effective in the rapid delivery of drugs, using the oral route as a site of administration.

  • 5 June 2013
    Requirement of M. S. (Pharm.)/ M. Pharm./ M. Tech. for the post of Jr Research Fellow in UTU

    Applications are invited from young and meritorious Indian citizens for filling up one position of JRF funded by the Department of Biotechnology (DBT), Govt. of India. The current project ongoing draw from recent high throughput-drug discovery campaigns, “Antifolate hit-to-lead optimization for PfDHFR-TS inhibition”.

  • 12 May 2013
    A REVIEW : APPROACH IN DENTAL DRUG DELIVERY SYSTEM

    ABOUT AUTHORS:
    Badola Ashutosh,* Nishu Sharma
    Shri Guru Ram Rai Institute of Technology & Science ( SGRRITS ),
    Dehradun 248001, Uttarakhand , India
    *ashutosh.badolam.pharma@gmail.com

    ABSTRACT:
    Controlled release local drug delivery systems offer advantages compared to systemic dosage forms for periodontitis. The objective of this research was to design and evaluate sustained release dental films containing drug in a non-biodegradable polymer for targeted delivery of the drug. The polymer ethyl cellulose was used in the formulation of dental films. The dental film was then evaluated for various parameters like thickness, folding endurance, and weight variation, and content uniformity, in vitro and in vivo study. Drug release profile of the dental film showed that the film exerted an initial burst release followed by a sustained release of the drug and the drug release was well above the minimum inhibitory concentration throughout the time of study. The release data obtained were subjected for release kinetics study. The study suggested that the non-biodegradable based dental film is a potential local drug delivery device for the treatment of periodontitis.

  • 3 May 2013
    Walk in interview for B.Pharm, B.Sc for Medical Representative, Area Sales Manager in Novation Labs India - Multiplace vacancy

    Novation Labs India is a Leading, Upcoming & Professionally Managed Pharmaceutical Company deals in Super Specialty of Neurology Division & Cardio Diabetic Division.

    Post: Medical Representative, Area Sales Manager

    [adsense:336x280:8701650588]

  • 15 March 2013
    PULMONARY DRUG DELIVERY: A REVIEW

    ABOUT AUTHORS:
    Dr. N.V. Satheesh Madhav, Girish Dwivedi*
    Dehradun Institute of Technology, Faculty of Pharmacy
    Village Makkawala, Mussoorie Diversion Road,
    Dehradun-248009
    *Girish10.dwivedi@yahoo.com

    ABSTRACT
    Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung both for site specific and systemic treatment. The review is prepared with an aim to discuss about the technical, physiological, and efficacy aspects of the novel pulmonary route of drug targeting and different delivery devices such as metered dose inhalers (MDI), dry powder inhalers (DPI), nebulizers, etc. The review also focuses on the mechanisms of pulmonary drug administration along with compatibility of the excipients employed, devices used, techniques of particulate dosage production, evaluation and advancements in the pulmonary drug delivery. It can be concluded from whole study that different pulmonary delivery system possesses certain specificity for dosage formulations and serves as an important tool to deliver drugs to the target site.

    [adsense:336x280:8701650588]

  • 1 March 2013
    Acne (Pimple) Treatment at Dr. Batra's

    Rasa

  • 20 February 2013
    Faculties invited in Sardar Bhagwan Singh Post Graduate Institute of Bio-Medical Sciences & Research

  • 5 February 2013
    Application are invited from Junior Research Fellow in BSI | 22 Posts

    Applications are invited from Indian Nationals for appointment of Junior Research Fellows (JRFs)

    Post: Junior Research Fellow

    [adsense:336x280:8701650588]

  • 31 January 2013
    Opportunity for B.Pharm / M.Pharm as Executive - Contract Manufacturing in Evolet Healthcare - 2 vacancies

    Evolet group comprise of Four Marketing Companies in Europe and one Logistic Company. As Evolet we are having our offices in Europe, China, CIS and India, We are working in India as an export company through contract manufacturing with some of the big companies in India Like Nectar Life Sciences, Akums Drugs, Ind-Swift Labs, Elder Pharmaceuticals Ltd, Ahlcon Parentrals etc.
    We are also having our partners in many countries in Europe through whom we work on contract manufacturing.

  • 1 January 2013
    DENDRIMERS FOR NOVEL DRUG DELIVERY: AN OVERVIEW

    About Authors:
    Roopesh Sachan    *1, Prof. Satyanand Tyagi2, Tarun Parashar1, Soniya1, Patel Chirag J*3,Patel Pinkesh3, Rishikesh Gupta4
    1    *Department of Pharmaceutics, Himalayan Institute of Pharmacy and Research, Rajawala, Dehradun, Uttarakhand, India-248007.
    2    President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
    3    Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
    4    Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India-284128.
    *roopeshsachan@gmail.com, +91-9557469989, 9236167104

    ABSTRACT:
    Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc.The field of Dendrimers has recently emerged as the most commercially viable technology of this century because of its wide-ranging potential applications in many fields such as: healthcare, electronics, photonics, biotechnology, engineering products, pharmaceuticals, drug delivery, catalysis, electronic devices, environmental issues and nanotechnologies. Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery option.

Subscribe to Dehradun