Noida

HLL Lifecare Limited is a Mini Ratna Company of Govt. of India under the Ministry of Health & Family Welfare. HLL, a schedule B Public Sector Enterprise is today a multi product, multi unit organization addressing various public health challenges. The company with five manufacturing units and marketing offices throughout the country is engaged in the manufacturing and marketing of a wide range of contraceptives and healthcare products. The company has also ventured into Infrastructure Development, Procurement & Consultancy Services, setting up of Life Spring Hospitals, Women's Health Pharma Division and setting up of Diagnostic Centres.

Post: Pharmacist/Assistant Pharmacist, Pharmacy Assistant

HLL Lifecare Limited (HLL), India's leading manufacturers and marketers of contraceptive, Health Care and Pharma products is a Mini Ratna Central Public Sector Enterprise under the Ministry of Health and Family Welfare.

Post : Area Sales Manager, Business Development Executive, Assistant Regional Manager

Kusum Healthcare Pvt. Ltd. was founded in 1997, as a 100 % export-oriented unit, with its headquarters in New Delhi.The company's first formulation plant was started in Bhiwadi, Rajasthan in 2007. Another formulation plant is expected to come up shortly in Indore, Madhya Pradesh. Kusum Healthcare Pvt. Ltd. is part of Kusum group of companies which is fully integrated, young pharmaceutical group on fast track having two manufacturing units; one of them is Kusum Healthcare at Bhiwadi Rajasthan India and the second is Kusum Pharm at Sumy Ukraine. Both these manufacturing units are WHO GMPcertified and PIC/s compliant.

Post: Medical Representative/ Field Sales Officer

Central Council for Research in Homoeopathy (CCRH) was established as an autonomous organisation in 1978, under the Dept. of AYUSH, Ministry of Health & Family Welfare, Govt. of India. Primarily a research body, CCRH has a multi-dimensional approach to research and its varied research activities include ‘Survey, collection and cultivation of medicinal plants’, ‘Drug standardisation’, ‘Drug proving’, ‘Clinical verification’ and ‘Clinical research’. Besides, CCRH also collaborates with other research bodies for researches and monitors extramural researches.

Institute of Good Manufacturing Practices India, registered as a non-profit society (under Societies Registration Act, 1860) with Government of India and a member (as a higher/professional education Institute) of Quality Council of India (QCI), Government of India -presents unique, friendly and interactive platform to get rid of all your GMP related glitches.

Bigchemist.com is an online ecommerce company which has specialization in pharmaceuticals and other FMCG products.
BigChemist was formed on the grounds of giving simple, effective solutions to health enthusiasts. It’s an ecommerce company with specialization in pharmaceuticals along with baby care and personal care products.

At United Health Group, their mission is to help people live healthier lives. To achieve this goal, they are focused on building a modern, adaptable, innovative and inclusive system of health care services.
Their scale and potential to improve health makes them one of the most visible stewards of America’s vast health care system. Entrusted with both important resources and responsibilities, they are involved on a daily basis in decision-making that has life-changing consequences for millions of Americans.

Incorporated in the year 1995, at Bahadurgarh (Haryana, India), “Ayusearch Drugs & Laboratories” is recognized Manufacturer, Supplier & Exporter of premium quality Ayurvedic medicines, Allopathic Medicines and Nutraceuticals. The products that we bring forth include Tablet, Capsule, Syrup, Powder, Granules, Ointment, Paste, and Cream.

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ABOUT AUTHORS
Abdul Waheed*, Swati Pathak, Roohi Mirza
Department of Pharmacology,
Amity Institute of Pharmacy,
Amity University, Noida, U.P., India
*abdul.waheed2050@gmail.com

ABSTRACT
Epilepsy is a chronic brain disorder characterized by tendency to recurrent seizures or fits. The seizures can leads to loss of consciousness, disturbance of movement, muscle spasms, autonomic and mental functions. Epilepsy is developed because of imbalance in nerve signalling chemical called neurotransmitters. During epilepsy, the level of excitatory neurotransmitter glutamate increases and the level of inhibitory neurotransmitter GABA decrease. These lead to abnormal signalling in brain causes epilepsy. Primary diagnosis of epilepsy includes eye–witness and family history. Electroencephalograph (EEG) is the cornerstone for diagnosis of epilepsy and measures the brain wave activity. Neuroimaging like computed tomography (CT) scan, magnetic resonance imaging (MRI) and positron emission tomography (PET) techniques are used to diagnose abnormalities in structure and function of brain. Video recording is also useful for the monitoring of epileptic events. The most common approach of treatment is to prescribe antiepileptic drugs (AEDs). Three generations of AEDs including phenytoin, valproate, carbamazapine, lamotrigine, Oxcarbazepine, Primidone,Phenobarbitone,Gabapentin, Topiramate, Levetiracetam, Felbamate, Rufinamide, Zonisamide, Tiagabinand Vigabatrin etc. are prescribed. These AEDs have some teratogenic effects on  pragnent woman and lactating mother; need precautions. Instead of  pharmacological approaches, Non-pharmacological approaches also used for the treatment of epileptic seizures like ketogenic diet, atkins diet, yoga etc. Thr purpose of this review is to update the current knowledge on epilepsy classification, diagnostics, approaches of treatment, pathophysiology, mechanism of epileptogenesis and teratogenic effects.