Pharmapedia

13 November 2014

Pharmaceutical Market Research and Analytics
About Author:
Knowledge Perks,
Gurgaon, Gandhinagar, India
knowledgeperks@gmail.com

Almost 10 years back two major trends led to the development of ever growing analytics industry.

First was the development of high end computers and smart analytics software’s (Paid as well as open source software’s

Increase in data being generated due to revolutions like social media, blogs, internet, social networks, computerized retail outlets etc.

Increasing trust of west into talent available in India which resulted in more complex, work which involves critical decision making too being outsourced to India
3 November 2014

Are laws required to treat diabetes mellitus (diabetics) and obesity (obese people)?

Editorial, Nov 2014 issue

“At present perhaps Japan is the only country where majority of the people are willingly assisting government by following Metabo law guidelines to shed those extra pounds or to be away from gaining those extra calories.
6 October 2014

DR.SUBHAS MUKHERJEE AND INDIA’S FIRST TEST TUBE BABY

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ABOUT AUTHOR:
Avlikant J. Dhawale*
RedCross Formulation, Ajanta Pharma, Aurangabad, Maharashtra
Department of Biochemistry, Gramin Science College (Swami Ramanand Tirth Marathwada University), Nanded, Maharashtra, India
*dhawale111@gmail.com

ABSTRACT:
Infertility is the inability of an animal or plant to reproduce by natural means. Many people in the world are facing the problem of infertility altimatlely the problem of saving their generations. Today, modern science chalanged and solved the problem of infertility by developing the technique of Test Tube Baby by using principle of in-vitro fertilization.

Dr. Subhas Mukherjee, first Asian who invented most easy and successful method of producing Test Tube Baby. In Culcutta, West Bengal, on 3rd October 1978, the team announced the birth of World's Second Test Tube baby named as 'Durga' (Kanupriya Agarwal). The announcement came 67 days after the birth of World's First Test Tube Baby named as 'Louise Brown in England by Physiologist Robert G. Edwards who awarded the Nobel Prize for such work in 2010. During his lifetime, Government of West Bengal didn't recognized his work. By the day to day insult from government Dr. Subhas Mukherjee committed to suicide.
3 October 2014

Time to create a bridge between Pharmaceutical education and present Industrial demand

Editorial, Oct 2014 issue

“ Do you know why IIT students get more priorities in industry because their focus is to discover industry demand and coming out with a probable solution back by an extensive research work. Are pharmacy students learning challenges faced by pharmaceutical industry ?
28 July 2014

A REVIEW ON SOME OF THE BANNED DRUGS WHICH ARE STILL AVAILABLE IN INDIA

ABOUT AUTHORS:
Ramjith.U.S*, Tejil Mathew
Nazareth College of Pharmacy, Othera,
Thiruvalla, Pathanamthitta, Kerala.
ramjithganesh143@gmail.com

ABSTRACT
There are a broad category of drugs used for several disorders (diabetes, cancer, arthritis etc). A number of drugs that are banned in abroad are freely available in the Indian market. The most pitiable feature is that use of these drugs is regularly causing long term implication for our physical health. Some of the common ones that are easily available and people use frequently without doctor’s prescription are cisapride, pioglitazone, sibutramine, phenylpropanolamine, tegaserod, gatifloxacin, rofecoxib, rosiglitazone, nimesulide and analgin. Analgin, nimesulide, rofecoxib are non steroidal anti-inflammatory and analgesic drugs which on long term use can affect human health in various ways by damaging liver, causing irregular heartbeats, depression, blood pressure fluctuations etc. This is the prime reason that most of European countries have disqualified and banned the manufacturing and consumption of these drugs. It has been recently pointed out that Indian drug regulatory authorities have refused to ban sale of 10 drug, including gatifloxacin, rosiglitazone, rofecoxib, apart from over 80 drug combinations that are prohibited in other countries IPA have made various regulations and guidelines for the control of these drug, but still they are in use because of lack of awareness in people. So by this review we try to create awareness among people regarding the banned drugs and there reason for ban.

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4 March 2014

IDENTIFICATION OF BACTERIAL SPECIES BY COMBINED BIOINFORMATIC AND POLYMERASE CHAIN REACTION

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About Authors:
Emanual Michael Patelia, Bushra Ahmed, Muhammad Javaid, Jayesh Patel, Rakesh Thakur, Mishra Trinath
Department of Pharmacology, University of Bedfordshire, England,
United Kingdom, LU1 3JU
ricky.emanual@gmail.com

Abstract
The identification will be carried out by comparing a potential PCR product obtained from an unknown species with other PCR products specific to 5 known species, using the same five set of pairs of primers specific of these five species respectively. This implies that each PCR product obtained for each species has to be specific to each species and can be considered as a marker in this exercise. This specificity will be based on the uniqueness of the chosen template that is to be used for each PCR. In addition, since the PCR products will not be sequenced, they will be differentiated by their size, which will be identified by agarose gel electrophoresis. The PCR product can only be used as a marker that defines a species if the amplified sequence is unique to this species. Therefore, the first step in this exercise will be to identify a suitable sequence to amplify for each species. Following the identification of a suitable template, the size of the PCR will have to be defined; since the comparative analysis will be based not only on the presence of a product but also its size, all PCR products should have different sizes identifiable on agarose gel. Since the size of a PCR product is defined by the location of primers along the sequence, the second step in this exercise will be to design suitable primers. Finally, having defined specific template and primers for each species, PCR will be carried out using the DNA of unknown species as a template with all five sets of primers so that a successful PCR product and its size would identify the unknown species as one of the five species.
23 February 2014

RATIONAL USE OF MEDICINES: CAN WE PROMOTE

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About Authors:
Languluri Reddenna
Department of Pharmacy Practice,
Rajiv Gandhi Institute of Medical Sciences,
Kadapa, Andhra Pradesh, India-516003
reddennapharmd@gmail.com

Abstract
Rational use of drugs can be defined as prescribing the right drug, in sufficient dose for the adequate duration and suitable to the clinical requirements of the patients at least cost. Causes of irrational use comprise not have of knowledge, skills or self-determining information, unhampered accessibility of medicines, overburden of health personnel, unsuitable promotion of medicines and earnings motives from selling medicines. In appropriate drug usecan have dire consequences; it has been associated with hospitalization and evencaused deaths of inpatients in health carefacilities. A variety of situations and circumstancespromote irrational use of medicines. Rational use of medication saves lives, confines undesired toxicity, adverse events and maximize on the benefits that can be imitative from best use of medications. According to surveys conducted in 2004 by HAI Africa and WHO in 11 Sub-Saharan Africa countries in 2004, the average accessibility of the essential medicines in public health facilities was below 70%. Communication between professionals and consumers is essential to the enhancement of rational use of medicines. It is essential to recommence collaboration of physicians and pharmacists concerning accurate and competent drugs prescribing. Governments, private health care institutions, entity health care providers and patients all have an accountability to endorse rational use of medicines. Professionals should provide information to the customers about the name of the medicine, the intention for which the medicine is being taken, dose, frequency of use, and duration of use.

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11 February 2014

SOY-BASED DIET: A MESMERIZING TRIUMPH FOR WELLNESS

There are three topics that can cause derision and division at any coffee or dinner table across the Western world: religion, politics, and soy. The humble soybean does have a noble and ingrained place in our world today and, whether you are pro or no, it’s almost unavoidable. Soy is everywhere - from your soy milks and tofus to the more discreet soy lecithin used to prevent compounds from separating during the cooking process.
9 February 2014

CHALLENGING ROLE OF PHARMACIST IN HEALTH CARE THE FUTURE PROSPECTS

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MODERN PHARMACIST:
One who is able to provide the patient oriented services as in developed countries is called as a modern pharmacist. Such services start from obtaining patients medication history to the feedback from the same after discharge. The componential characteristics that a modern hospital pharmacist must possess include:
1. Professional knowledge
2. Computer / IT acquaintance & skill
3. Counseling and communication skills
16 January 2014

NEXT LIPITOR WILL ALSO BE FROM METABOLIC THERAPY

Introduction
At least one article is seen in newspaper on obesity on daily basis; no other disease is searched (and articles are read on) as frequently as obesity. Such is the menace of obesity that even fast food giant McDonald's has put an advice in few of its offices “not to eat too much fast-food”. Obesity is defined as BMI (body mass index) 30kg\m2 or more. A person with a BMI between 25 and 29.9 are considered over weight but not obese. BMI is a simple index of weight-for-height that is commonly used to classify overweight and obesity in humans. It is also defined as a person’s weight in kilograms divided by the square of his height in meters (kg\m2). As per world health organization (WHO), BMI greater than or equal to 25 is overweight and BMI greater than or equal to 30 is obese. Obesity is a foremost health problem not only in developed nations but also in developing countries. It increases the risk of other diseases like diabetes, cardiovascular ailments, fatty liver and some forms of cancer1.

Obesity is now so common in various geographies that it is beginning to replace conditions arising from malnutrition and infectious diseases as the most significant contributor to ill health. Obesity is measured using BMI and further evaluated in terms of fat distribution via the waist–hip ratio and total cardiovascular risk factors2. BMI is closely related to both percentage body fat and total body fat3. The global epidemic of obesity results from an amalgamation of such factors as genetic susceptibility, increased availability of high-energy foods and diminished need of physical activity in prevailing situation in modern society. Obesity is no more a cosmetic issue affecting certain individuals, but a pandemic threatening global well being because it exacerbates a large number of health-related problems, both independently and in association with other ailments^4,5.