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Serum : Effective mode with high concentration of actives

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Serum Effective mode with high concentration of actives

Vinay KumarVinay Kumar Singh. 
Head-Formulation
Kumar Organic Products Research Centre Pvt. Ltd.,
Bengaluru
Email : formulation_krc@kopresearchcentre.net

Many things improve with age; unfortunately, our skin is not one of them. Wrinkles, brown spots, and general dullness often start to creep in as the years tick by. To reverse these problems many are turning to a skin serum. Serum is a concentrated product which is widely used in Cosmetology. A serum is a lightweight liquid with a viscous texture that can target a number of different skin concerns, a few being acne, dullness, clogged pores and dryness, wrinkles or dark spots. Serums contain a higher concentration of active ingredients than other skin care products to target specific skin concerns. Also, due to the higher concentration, it typically takes a shorter amount of time to see visible results. Typically, it is okay (and recommended) to use face serum daily. Depending on the type of serum, one may want to use a retinol serum only a couple of times a week to avoid irritation, while something like a vitamin C or hyaluronic acid serum is recommended for daily use. Most serum formulations mainly feature Hyaluronic Acid, Retinol, Vitamin C, and Glycolic Acid to battle skin concerns such as acne, lines, wrinkles, hyperpigmentation, etc.

Unlike your moisturizers or face gel, serums are thinner in consistency as they are formulated with smaller molecules and no heavy oil. They have up to 70% active ingredient concentrations, making them the affluent skin care products in beauty. 
Serum therapy for pneumonia was a revelation when it appeared in the 1930s, and it saved thousands of lives before being replaced by penicillin.

Reference Id : PHARMATUTOR-ART-3015


Egyptians applied a variety of plant-based oils on their skin. Sesame oil, castor oil, and olive oil were some of these priceless elixirs. The legendary queen Cleopatra, renowned for her everlasting beauty and relationship with Julius Caesar, is supposed to have preferred olive oil and sesame oil for her grooming regimen. These oils had two uses in prehistoric Egypt. They offered protection from the harsh desert conditions in addition to enhancing the skin's beauty. These early mixtures, with their nourishing and renewing qualities, served as the prototype for what we today refer to as face serums.

As defined in the dictionary – a serum is the clear, yellowish fluid obtained upon separating whole blood into its solid and liquid components after it has been allowed to clot, so it is not surprising that the precursors of modern-day serums were based on horse blood, egg albumin, and bovine placenta. Packaging these products in sterile ampoules preserved with oxyquinoline (and later, the invention of parabens) made them available commercially. This is a practice that stayed with us since the early days of short product shelf life, which meant small batches had to be made and used up quickly before the product spoiled. Exercise, cleanliness, and skincare were all held in high regard during the 1800s.


Ideal Qualities of Face Serum 
1.Soothes irritated skin: It is well known that aloe vera possesses antiviral and cell-regenerating capabilities. The advantages of aloe gel are comparable to how applying it to a sunburn feels. 
2. Deep hydration: possess a special capacity to raise and decrease skin moisture.
3.Fight Acne and fades blemishes: Bael fruit extract stops the bacterial overgrowth that is the primary cause of acne and pimples.
4.Remove dark circle and puffiness: Vitamin E and antioxidants in abundance aid with eyelid discolouration, and the cooling impact reduces puffiness. It makes under-eye circles look less prominent. It removes dead skin cells, which encourages the synthesis of collagen.
5. It contains antioxidant qualities that encourage healthy-looking skin 
Advantages of Serum
• Improves skin texture. 
• Minimizes the skin pores. 
• Hydrates and nourishes the skin. 
• Improves skin elasticity.
Disadvantages of Serum
• The liquid or gel-like texture of a serum can be a poor match for people with chronic skin conditions like eczema or rosacea, which weaken the skin barrier. • For these people, serums may penetrate too quickly, causing irritation

Types of face serum 
1. The oil serum: The oil serum is the simplest to make of all the face serums. It often starts with a base of just premium, fastabsorbing carrier oils, also referred to as "dry" oils. In addition to having moisturising and barrier-repairing characteristics, the premium oils used in the serum also include polyphenols, essential fatty acids, and other substances that may be broken down by the skin.
2. The gel serum: Gel serums provide the skin a "tightening" sensation, giving  consumer the impression that their skin is momentarily lifted or tightened in particular regions of the face. The gel serum provides you the chance to include some fantastic water-based (hydrophilic) plant extracts or Bioferments because this formulation is water-based,
3. The Water based serum: Water-based serums are comparable to gel serums, although they may contain none or very little gums and thickeners. To administer high-performance hydrophilic plant extracts or Biofermets, that are trapped against the skin beneath a cream or lotion, one would utilise a water-based face serum. Layering an anti-ageing face mist under an emulsion and then under an oil is the ideal technique topromote higher penetration of water-based compounds into the skin, delivering their high performance elements slightly deeper into the layers of the skin. The oils will form an occlusive barrier that will promote higher component penetration.
4. The emulsion serum: An emulsion-based face serum is a moisturiser that strengthens the skin's barrier function while also delivering high performance components to the skin. Two "immiscible" phases-phases like oil and waterthat don't want to mix-are combined in an emulsion. An emulsifier is used to bind water and oil together and retain them in a stable state. The best chance of delivering high performance actives deeply into the tissues of the skin is through an emulsion. Given the skin's barrier function, it is highly difficult for any cosmetic component to penetrate dermis, yet an oil and water mixture is best suited to accomplish this remarkable feat. The skin's barrier function will be strengthened by the emulsion's moisturising characteristics.
5. The pressed balm serum: A balm serum has a conventional balm basis of butters, waxes, and oils but also includes active substances that are oil-soluble (lipophilic) and may help the skin. The butters and waxes form an occlusive barrier on the skin that hydrates and nourishes it while allowing the pressed serum's active components to do their job. In a balm serum, dozens of intriguing unique butters and waxes can be combined with thousands of exquisite plant oils.
In general, face serums fall into the following categories based on its function or property.

Anti-aging serums : Anti-aging regimens encourage skin renewal and collagen production. This type of serum often includes retinol or bakuchiol, or both.e.g. Neutrogena Rapid Wrinkle Repair Night Moisturizer, CeraVe Skin-Renewing Retinol Serum
Skin-brightening serums: Skin-brightening serums are often chock-full of antioxidants and pigment-fighting ingredients to improve skin tone.Key ingredients might include things such as vitamin C, glycolic acid, kojic acid, ferulic acid, mushroom extract, licorice root, or lactic acid, among others.e.g. L’Oreal Paris Revitalift 10% Pure Vitamin C Concentrate, CeraVe Vitamin C Skin Renewing Serum.
Hydrating serums : Hydrating serums contain hyaluronic acid, a molecule that physically binds water in the skin to make it look fresh, plump, and younger.Kids make lots of hyaluronic acid, and it’s attached to their collagen, but as we age, we lose collagen and lose the attached acid.Topical serums with hyaluronic acid can temporarily bind water in the superficial layers of the skin, which can make our skin appear fresher and dewier. It also has the ability to temporarily minimize the appearance of fine lines.
Hydrating serums often contain vitamin B5, which helps to hydrate skin, making it appear smoother and more hydrated.e.g. SkinMedica HA5 Rejuvenating Hydrator, Neutrogena Hydro Boost Hydrating Serum
Free-radical fighting serums: Antioxidants fight free radicals that can damage healthy skin.To help prevent skin damage from free radicals, choose a serum that contains ingredients like vitamins C, A, and E, and resveratrol.e.g. SkinCeuticals C E Ferulic Serum, Drunk Elephant D-Bronzi Anti-Pollution Sunshine Drops
Acne and sensitive skin serums : Anti-acne serums often contain salicylic acid or similar plant-based derivatives.It also contains niacinamide (a form of vitamin B3), which is a soothing, hydrating, and anti-inflammatory ingredient that’s combined with other active ingredients to minimize irritation and soothe sensitive skin.e.g. Paula’s Choice Niacinamide Booster 10%.
Skin texture serums : To help boost our skin’s texture and the overall appearance of your skin, a serum with glycolic acid can be used.This sugarcane-derived alpha hydroxy acid can penetrate the top layers of the epidermis to disrupt the intercellular bonds. It can also help shed the dulling, discoloured, dead cells to reveal smoother, glowing skin with more uniform texture, tone, and colour.e.g. L’Oreal Paris Revitalift 10% Pure Glycolic Acid, NO7 Lift &Luminate Triple Action Serum

A serum for the face should be one of the most integral parts of anyone’s skincare regimen. This highly concentrated skincare product offers multiple benefits related to hydration, nourishment, and the protection of skin cells. 
1. Improved skin texture
Serums help improve the skin’s texture, making it firmer and smoother. Since they penetrate deeper into your skin’s epidermis, they treat the problem right where it manifests. For example, a serum containing hyaluronic acid slows down signs of premature aging while one containing Vitamin C helps with collagen production.
2. Combats acne
Using vitamin c face serum for acne-prone skin is the easiest and most direct way to deliver nutrition to the skin. It is highly productive in treating pimples and reducing inflammation. It would also take out whiteheads and blackheads, besides reducing skin pores and giving your skin a fresh and moisturized look. 
3. Moisturizes, nourish, and brighten your skin
For your daily dose of skin nourishment, serums are enriched with the goodness of hyaluronic acid and aloe vera. These ingredients improve the skin’s elasticity when layered underneath a toxin-free face cream. They also make it smoother, suppler, hydrated, and radiant in all seasons. 
4. Get you rid of dark spots
Exposure to UV rays causes the skin to produce more melanin and appear dark in some areas. This is where using Vitamin C Skin whitening serum comes to the rescue. Vitamin C helps reverse signs of sun damage on the skin, inhibits melanin production, and makes your skin appear glowing and bright. The concentrated ingredients in the formula lighten dark spots and blemishes and make your skin radiant and glow.
5. Keep fine lines at bay
Someday, we all would get wrinkles and fine lines owing to our age. While they cannot be removed permanently, they can be slowed down and minimized using an effective anti-aging skincare regimen. By using some of the best skin brightening serums, one may feed one’s skin with anti-aging oxidants to encourage collagen production, thus warding off fine lines and wrinkles. One can also use Salicylic Acid Serum with neem for Clear Skin.
We, at Formulation department of Kumar Organic Products Research Centre, Bangalore have formulated following Serum.
Intense hydrating serum with Kopulan(Pullulan) , Koprosteine(:L-(-)-2-Oxothiazolidine-4-carboxylic acid) &Kopuron (Sodium Hyaluronate )
Antiageing serum with Kopsoyatol (Soya bean ferment filtrate )
Carrot dew with Kopcarotol (Carrot root ferment filtrate )
Skin rejuvenating serum with Kopraditol(Radish root ferment filtrate)
Face serum with Kopuchiol (Bakuchiol)

In conclusion, the evolution of face serums is evidence of the age-old pursuit of beauty and self-care. Serums have advanced significantly throughout the years, from the Cleopatra-favoured Egyptian elixirs to the modern, cutting-edge formulas. It is impossible to overestimate their significance in current skincare regimens. Use a serum if you value your appearance and yourself. It's more than just a product. 

It is a dedication to keeping our skin healthy and beautiful for years to come. So, take the first step towards glowing skin and let a premium serum be your dependable companion on the road to classic beauty.