Pharma News

The U.S. Food and Drug Administration approved Ogsiveo (nirogacestat) tablets for adult patients with progressing desmoid tumors who require systemic treatment. Ogsiveo is the first drug to be approved for the treatment of patients with desmoid tumors, a rare subtype of soft tissue sarcomas.

An innovative stem cell-based treatment for Type 1 diabetes can meaningfully regulate blood glucose levels and reduce dependence on daily insulin injections, according to new clinical trial results from the University of British Columbia (UBC) and Vancouver Coastal Health (VCH).

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases. But the lack of effective ways to deliver biological treatments into the body has posed a major barrier for bringing these new therapies to the market — and, ultimately, to the patients who need them most.

Hair products often contain ingredients that easily evaporate, so users may inhale some of these chemicals, potentially posing health repercussions. Now, researchers have studied emissions of these volatile organic compounds (VOCs), including siloxanes, which shine and smooth hair. The scientists report in ACS’ Environmental Science & Technology that using these hair care products can change indoor air composition quickly, and common heat styling techniques straightening and curling increase VOC levels even more.

As per the recent study in South Africa, it is concluded that service delivery and sales productivity have been enhanced as a result of technology adoption by salespeople.

Drugmakers are seeking to limit their reliance on Chinese contractors who produce drugs used in clinical trials and early-stage manufacturing, a move that is benefiting rivals in India, according to interviews with 10 industry executives and experts.

Scientists at St. Jude Childrens Research Hospital showed that GRP78 is a promising, but complex, target for CAR T-cell immunotherapy for brain and solid tumors.

In Alzheimer’s disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau. Wherever tau builds up, nearby brain tissue starts to degenerate and die. 

The research environment at UiT The Arctic University of Norway has found a bacteriocin that can help inhibit the growth of antibiotic-resistant bacteria. "An exciting discovery", says researcher Runa Wolden at the Department of Clinical Medicine.