TOXICOLOGICAL SCREENING OF ‘GOWRI CHINTHAMANI CHENDOORAM'- A SIDDHA METALLIC PREPARATION
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ABOUT AUTHORS:
Shanmugapriya.P1, Thamodharan.S1, M.Ramamurthy2, V.C. Jiji Mol3, M. Nijavizhi3
1 Department of Nanjunool, National instistute of siddha, Chennai, Tamil Nadu, India
2Assistant medical officer, Salavakkam
3PG scholars, National institute of siddha, Chennai, Tamil Nadu, India
drjijivijay@gmail.com
ABSTRACT
'Gowri chinthamani chendooram', a siddha drug was evaluated for its acute and chronic toxicity studies in wistar albino rats with reference to haematological, bio-chemical and histopathological studies. Acute study revealed a maximum tolerated does of 640 mg/100 gm b.w chronic toxicity study revealed a minimum toxic effect at adoes level of 40 mg/100 gm b.w. Where in, the changes observed were non-specific. The toxicity findings were dose specific, which had tissue damage in higher dosages.