Evonik, one of the world's leading specialty chemicals companies, is making a significant investment to strengthen manufacturing capabilities at its Tippecanoe Labs site in Lafayette, Indiana. The site is home to one of the world's largest facilities for the production of active pharmaceutical ingredients (APIs), the industry's biggest high-potency API operation, and a major employer in the Greater Lafayette region.

1. A non-volatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection, it produces general anaesthesia for 10 minutes. Which process is responsible for termination of its action?
(a) Metabolism in liver
(b) Excretion by kidney
(c) Plasma Protein Binding
(d) Redistribution

2. Aspirin overdose is characterized by:
(a) Hyperthermia, metabolic acidosis and coma
(b) Fever, hepatic dysfunction and encephalopathy
(c) Rash, interstitial nephritis and acute renal failure
(d) Rapid, fulminant hepatic failure