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DEVELOPMENT AND VALIDATION OF ANALYTICAL METHODS FOR SIMULTANEOUS ESTIMATION OF AMITRIPTYLINE HYDROCHLORIDE AND METHYLCOBALAMIN IN THEIR TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRIC METHOD

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ABOUT AUTHORS:
Chetna V. Karchaliya*, Parula B. Patel
Department of Quality Assurance,
S. J. Thakkar Pharmacy College,
Rajkot, Gujarat, India
*sonichetna158@gmail.com

ABSTRACT:
The simple, accurate and precise Absorption Correction Method has been developed for the simultaneous estimation of Amitriptyline hydrochloride and Methylcobalamin in combined tablet dosage form. The method utilizes distilled water as solvent and λmax of Amitriptyline hydrochloride and Methylcobalamin selected for analysis were found to be 239 nm and 351 nm respectively. The method was validated as per International Conference on Harmonization (ICH) guidelines. The Linearity range lies between 20-60 µg/ml (R2 0.9998) for Amitrityline hydrochloride and 3-9 µg/ml (R2 0.9990) for methylcobalamin. The accuracy and precision were determined and found to comply with ICH guidelines. The method showed good reproducibility and recovery with %RSD in desired range. The proposed method can be applied for routine analysis of both drugs.

Ayurvedic Cosmetics

ABOUT AUTHOR:
Vinay Kumar Singh
General Manager-Technical,
Mikasa Cosmetics Limited,
Ahmedabad, Gujarat
vinay.s@mikasacosmetics.com

To understand Ayurvedic Cosmetics one must think as to what is the synergy between Ayurveda and Cosmetics. The word ‘cosmetics’ is derived from the Greek word ‘kosmeticos’ which means skill decoration or skill in arranging in order or correcting the deformities. Cosmetics is applied topically to skin and its appendages to cleanse, decorate, beautify, alter the appearance and ultimately to enhance confidence of user.

Career for Production (Dry Powder Injectables)as Deputy Manager / Manager with 7 to 8 yrs of Experience and interested working with Jodas Expoim Pvt Ltd.

Jodas India is manufacturing and sourcing arm of Moscow (Russia) based Jodas Expoim. Till date, most of the Jodas’s products are manufactured in India.

Post: Deputy Manager - Production (1)

Walk in interview for Research Scientist, Officer/Executive in Macleods

Macleods, India's Fastest growing pharmaceutical company, with a strong R&D, manufacturing sites ranked among the top pharmaceutical companies presently operating in more than 50 countries worldwide, requires talented professionals

Post: Research Scientist, Officer/Executive

Opening for Bio Analytical Research Analyst in Sai Clinical Research Institute

The Sai Clinical Research Training Institute is a unique year-long education and mentoring program for hematology fellows and junior faculty at academic medical centers and offers a broad education about clinical research methods, research collaborations, statistical analysis, and managing the demands of family and career.
The goal of Sai Clinical Research Training Institute is to produce a group of researchers armed with ideas for clinical hematology research and the tools and access to resources to make their ideas a reality.

Post: Bio Analytical Research Analyst

Work for B.Pharm, D.Pharm as Retail Pharmacist in HealthKartPlus | 5 Opening

HealthKartPlus is India's first and only Generic Drug Search Engine which enables you to find the best medicine for your treatment. It includes most of the brands as well as their generic equivalents which are cost effective.
HealthKartPlus is a highly functional application which acts as a search engine which is free of cost and is easily accessible. This revolutionary step aids in educating the consumers, providing them with the best alternative medicines to choose from.

Post: Retail Pharmacist

Walk in interview for Senior Research Fellow in National Dairy Research Institute

The Walk-in-Interview for the positions of Post Doctorate Fellows/Research Associate/ Senior Research Fellows/Junior Research Fellows and Field Investigator in below mentioned project/scheme will be conducted at this Institute on the date/time and venue and other details shown against positions on contractual basis, which is co-terminus with the project/scheme. The eligible candidates are invited to appear before the Selection Committee for Walk-in-Interview at NDRI, Karnal.

Post: Senior Research Fellow

FLUORIDE ADULTERATION IN DENTAL PRODUCTS

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ABOUT AUTHORS:
Nidha Amir*, Mohd Mazhar, Abhinav Sawhney, S.K Rajput
Department of Pharmacology
Amity Institute of Pharmacy, Amity University, NOIDA, Uttar Pradesh-201313, India
nidha.amir05@gmail.com

ABSTRACT
Fluorine, the 13th most abundant element of the earth’s crust, represents about 0.3g / kg of earth’s crust. It occurs mainly in the form of chemical compounds such as sodium fluoride or hydrogen fluoride, which are present in minerals fluorospar, fluorapatite, topaz and cryolitect. Fluoride is frequently encountered in minerals and in geochemical deposits and is generally released into subsoil water sources by slow natural degradation of fluorine contained in rocks. Fluoride being a natural element has several effects on health. Fluoride is beneficial to health if the concentration (CF) of the fluoride ion (F-) in drinking water is less than 1.5 mg/L (WHO 1994). A higher concentration causes serious health hazards. The disease caused manifests itself in three forms, namely, dental, skeletal, and non-skeletal fluorosis. On a large scale, it is used in dental product due to its anti- sensitizing property and abrasive action. Application of fluoride must be controlled and restricted to reduce the side effect induced by it.

Applications are invited for Senior Research Fellow in IIT (BHU) | M.Pharm

Applications are invited for the post of one SRF in DST Sponsored Project entitled “Development and Evaluation of Nanocarrier for Enhanced Antimicrobial Activity of Anacardic acid Against Human and Plant Pathogens” sanctioned up to three years. The post is purely temporary and co-terminus with the project.

Post: Senior Research Fellow

World Health Organization (WHO) Country office for India in collaboration with the Ministry of Health and Family Welfare, Government of India and National Health Systems Resource Centre (NHSRC), formally announced the commencement of National Health Systems Resource Centre (NHSRC), as the WHO Collaborating Centre for Priority Medical Devices and Health Technology Policy.

Job as Pharmacist in PHC Bandara, Odisha, Miao, Delhi and Bir Hospital.

The Department of Health, Central Tibetan Administration, Dharamsala invites application for a post of Pharmacist at PHC Bandara, Odisha, Miao, Delhi and Bir Hospital.

Post: Pharmacist

Opportunity for SRF in IIT (BHU)

Applications are invited for a post of Senior Research Fellow (SRF) in the fellowship of Rs. 18000/- per month for year one and two, 20000/- per month for the third year and HRA @ 20% fixed in DBT, New Delhi sponsored project “Design and synthesis is of Matrix metallo roteinase (MMP -2 & 9) inhibitors as therapeutic agents for Alzheimer’s disease” sanctioned for three years.

Post: Senior Research Fellow (SRF)

Career for B.Pharm, M.Pharm as Clinical Data Manager in HySynth BioTechnologies

HySynth BioTechnologies is a contract research organization based in Chennai, South India. We provide outsourced development services on a global basis to the pharmaceutical, biotechnology and medical device industries.

Post: Clinical Data Manager

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Opportunity for Regional Sales Manager in Bryogen Pharmaceuticals

Bryogen Pharmaceuticals Pvt Ltd is a leading Pharmaceuticals company with Dermatology, Critical Care, Oncology division

Post: Regional Sales Manager

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Work for M.Pharm as SENIOR PROJECT FELLOW (PHARMA) in HLL Lifecare

HLL Lifecare Limited, a Mini Ratna Central Public Sector Enterprise under the Ministry of Health & Family Welfare, Govt. of India is a global provider of high quality healthcare products & services. With state-of-the-art manufacturing facilities spanning across India, HLL is diversifying into vaccine manufacturing, lifecare services, sanitary napkins besides engaging in procurement consultancy, healthcare infrastructure development and facility management.

Post: SENIOR PROJECT FELLOW (PHARMA)- 02

Directorate, Medial Health Services, Dadra and Nagar Haveli invites Pharmacist, Cold chain & Vaccine Logistic Assistant | 4 Posts

Directorate, Medial Health Services, Dadra and Nagar Haveli, Silvassa invites applications from eligible candidates for the below mentioned posts to be filled on short term contract basis for Community Health Centres (CHCs) & Primary Health Services (PHCs), so as to reach the undersigned on or before 11/04/2015.

Post: Pharmacist, Cold chain & Vaccine Logistic Assistant

Advance technology in skincare

ABOUT AUTHOR:
Vinay Kumar Singh
General Manager-Technical,
Mikasa Cosmetics Limited, Ahmedabad

Skin care market in India is estimated to be more than Rs 7,000 crore as per Euro monitors report of 2013. Skin care is rapidly growing segment in India. Demand for skin care products will continue to rise as consumers start paying more attention to their skin. Consumers of all age groups look for benefits including wrinkle-free, smooth and glowing, and healthy skin.With changing life styles, increase in disposable incomes, greater product choice and availability, and influence of satellite television, internet, more people are taking interest in personal grooming. The facial skin care market is booming. Products are competing with one another to take shelf space in the retail stores. Facial skin care products have become an essential part of the beauty market. Like western countries, creams and potions are applied in India also, in an effort to remove the pimples and the acne, fight stress and worry lines, and to remain young..The trend is driven further by the launch of new products with additional benefits which persuades consumers to buy these brands. As a result, skin care witnessed growth by a value CAGR of 8% at constant 2013 prices.

Vacancy as Pharmacist in MSACS - Government Job

MSACS envisions an India where every person living with HIV has access to quality care and is treated with dignity. Effective prevention, care and support for HIV/AIDS is possible in an environment where human rights are respected and where those infected or affected by HIV/AIDS live a life without stigma and discrimination.

Post: Pharmacist- (ART Center, Civil Hospital Nandurbar & for WL)

Career for M.Pharm as Junior Technical Assistant in NIPER

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an 'Institute of National Importance'. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa. NIPER is a member of Association of Indian Universities and Association of Commonwealth Universities.

Post: Junior Technical Assistant

Walk in interview for the post of Research Fellow in ICTM

The Institute of Chemical Technology (ICT) Mumbai was established as the Department of Chemical Technology on 1st October, 1933 by the University of Mumbai, through active support of industries and philanthropists. The Institute was most popularly known as UDCT, Mumbai. Research has been an integral part of ICT since its inception and it has created over 500 first generation entrepreneurs. The UDCT grew significantly in stature and was granted autonomy under UGC regulations by the University of Mumbai and further converted in to an Institute on 26th January, 2002. Under the World Bank TEQIP programme, the Maharashtra government granted it full autonomy in June 2004. Due to the recommendations of the Government of Maharashtra and University of Mumbai, the ICT was granted Deemed University Status by the MHRD on 12th September, 2008, with all provisions of the UGC for funding and support as the state owned deemed university.

Post: Research Fellow

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