PharmaTutor (February- 2014)
ISSN: 2347 - 7881
Received On: 11/12/2013; Accepted On: 13/01/2014; Published On: 10/02/2014
Author: Surya Pratap Singh1*, Meenakshi Sahetya2, Mahaveer Prasad khichi3, Yogesh Yaduwansi4
1Department of pharmaceutics, Kota College of Pharmacy, Kota, Rajasthan, India
2Department of pharmacology, Kota College ofPharmacy, Kota,Rajasthan, India
3Head of department, Pharmaceutics, Kota College of pharmacy, Rajasthan, India
4 Research scholers,Kota College of pharmacy, Rajasthan, India
*sp.kota91@gmail.com
ABSTRACT: The purpose of this paper is to focus on drug delivery system developing by such polyelectrolytes and most focused on targeting of drugs to specific sites have aroused as revolution in pharmaceutical field, thereby, giving rise to drug delivery systems. Polymers have gained much importance in drug delivery especially those which respond in some desired way to change in pH, temperature, electric or magnetic field. For this reason they are very frequently and extensively used as excipients in design and advancement of controlled and/or sustained release products. The scope of polymers used in dosage form design can be increased by several approaches such as modification of their chemical structure, by combining different polymers in physical mixtures or by formation of polymer-polymer associations such as polyelectrolyte complexes.
How to cite this article: SP Singh, M Sahetya, MP Khichi, Y Yaduwansi, Polyelectrolytes: as a Drug Delivery System, PharmaTutor, 2014, 2(2), 44-51
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REFERENCES:
1. S Lankalapalli, V. R. M Kolapalli. Polyelectrolyte complexes: A review of their applicability in drug delivery technology”Indian journol of pharmaceutical sciences, 2009 ,71,(5), 481-487.
2. Josias H Hamman “Chitosan Based Polyelectrolyte Complexes as Potential Carrier Materials in Drug Delivery Systems”Marine drug-MDPI, 2010; 8(4): 1305–1322.
3. Molyneux,P., Water Soluble Synthetic Polymers: Properties and Behaviour,CRC Press, Boca Raton,Florida,1984.
4. Hoover, M.F., Cationic quarternary polyelectrolytes¬A literature review J. Macromol, Sci.-Chem.,1970.
5. Halverson,F & Panzer, R.E.Kirk and D, H.P.Flocculating agents. In Encyclopedia of Chemical Technology, 1975;10(3).
6. Kumar V, Yang T, Yang Y. Interpolymer complexation. I. Preparation and characterization of a polyvinyl acetate phthalate polyvinylpyrrolidone (PVAP-PVP) complex. International Journal of Pharmaceutics. 1999; 188: 221-232.
7. Lankalapalli S, Kollapalli VRM. Polyelectrolyte Complexes: A review of their applicability in drug delivery technology. Indian Journal of Pharmaceutical Sciences. 2009; 71(5): 481-487.
8. Dautzenberg H, Jaeger W, Kotz J. Philipp B, Seidel C, Stscherbina D. Polyelectrolytes: Formation, Characterization and Application. Polymer International. 1994; 38(1): 106.
9. Dobrynin AV, Rubinstein M. Theory of polyelectrolytes in solutions and at surfaces. Progress in Polymer Science.2005; 30: 1049-1118.
10. Krone V, Magerstadt M, Walch A, Groner A , Hoffmann D. Pharmacological composition containing polyelectrolyte complexes in microparticulate form and at least on active agent. United State Patent 5700. 1997; 459.
11. Bhupendra G. Prajapati, and Dr.Krutika K. Sawant, Poly Electrolyte Complex of Chitosan Alginate for Local Drug Delivery, International Journal of ChemTech Research,2009;1(3):643-648.
12. Yan XL, Khor E, Lim LY, Chitosan-Alginate Films Prepared with Chitosans of Different Molecular Weights. J Biomed Mater Res. 2001; 58(4): 358-65.
13. Kim HJ, Lee HC, Oh JS, Shin BA, Oh CS, Park RD, Yang KS, Cho CS., “Polyelectrolyte complex composed of chitosan and sodium alginate for wound dressing application” J Biomater Sci Polym Ed. 1999; 10 (5): 543-56.
14. Kok Khiang Peh and Choy Fun Wong, Polymeric Films As Vehicle For Buccal Delivery: Swelling, Mechanical, and Bioadhesive Properties”. J Pharm Pharmaceut Sci. 1999; 2 (2): 53-61.
15. Stefania racovit?, Silvia vasiliu and Cristina Doina vlad, New Drugs Delivery Systems Based On Polyelectrolyte Complexes Academia Român? Revue Roumaine De Chimie, 2010, 55(10), 659-666.