April 2017 ARTICLE LIST >>
PharmaTutor (April - 2017)
ISSN: 2347 - 7881
(Volume 5, Issue 4)
Received On: 20/12/2016; Accepted On: 28/12/2016; Published On: 01/04/2017
AUTHORS:
Susmita Das
Department of Pharmaceutical Technology,
Jadavpur University,
West Bengal, India
sdas53662@gmail.com
ABSTRACT:
The aim of the present study was to develop transdermal matrix patches with a fixed ratios of polyvinylpyrrolidone (PVP) and ethylcellulose (EC), containing the drug diclofenac sodium and to perform the physicochemical, in vitro relese pattern evaluation of the prepared patches. The prospective objective was the demonstration that the system provides the delivery of drug at a controlled rate across intact skin to achieve a therapeutically effective drug level for a longer period of time from transdermal patches.
How to cite this article: Das S;Preparation and In-Vitro evaluation of Diclofenac Sodium Transdermal Patches; PharmaTutor; 2017; 5(4); 46-54
[ABSTRACT WITH CITATION] [VIEW AS HTML]
REFERENCES:
1. Andrew GP, Lavarty TP, Jones DS.Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm. 2009; 71(3):25-29.
2. Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol. 2008; 26(11):1261-1268.
3. Gaiwak AK. Transdermal drug delivery system: formulation aspects and evaluation Com. J. Pharm. Sci. 2013; 1(1):1-10.
4. Dhiman S, Singh TG, Rehni AK, Transdermal patches: a recent approach to new drug delivery system, Int J Pharm Sci. 2011; 3(5):26-34.
5. Diclofenac transdermal patches: Medline Plus; https://medlineplus.gov/drug info/meds/a611001.html. Accessed on 6th December, 2016.
6. Bucci R, Magri AD, Magri AL. Determination of diclofenac salts in pharmaceutical formulations. Fresnius J Anal Chem. 1998; 362(7):2577-2582.
7. Ozgurey IS, Karasulu HY, Kantarci G. Transdermal delivery of diclofenac sodium through rat skin from various formulations. AAPS Pharm Sci Tech. 2006; 7(4):E1-E7.
8. Mukherjee B, Das S, Patra B, Layek B. Nefopam containing transdermal matrix patches based on pressure sensitive adhesive polymers. Pharm. Technol. 2006; 30(3):146-163.
9. Keith AD. Polymer matrix consideration for transdermal devices. Drug Deliv Ind Pharm. 1983; 9(4):605-621.
10. Sahu RK, Jain A, Nayak S. Development and evaluation of transdermal patches of colchicine. Der. Pharm. Lettre. 2012; 4(1):330-343.
11. Manasadeepa R, Paul P, Mukherjee B. Pressure sensitive mucoadhesive polymer based dental patches to treat periodontal disease: an in vitro study. Drug Deliv. 2013; 20(6):258-267.
12. Arora P, Mukherjee B. Design, development, physicochemical and in vitro and in vivo evaluation of transdermal patches containing diclofenac diethylammonium salt. J Pharm Sci. 2002; 91(9): 2076-2089.
13. Damodharan N, Roy G, Ghosh S, Mukherjee B. Skin permeation of rosiglitazone from transdermal matrix patches. Pharm Technol. 2010; 34(3):56-72.
.png)
