76) Which is used as gastric cytoprotective agent?
1. PGE1
2. PGF20!
3. PGE2
4. Misoprostol
77) 1. 4-Amino Quinoline
2. Acridine
3. Biguanide
4. Pyrimidine
78) In the pediatric dose calculation, children in the first twenty days of birth comes under the class of:
1. Infant
2. Child
3. Neonatal
4. Just born
79) Question Label: MCQ
Ths schedule to which 'List of drugs to be sold on prescription only1 belong to:
1. V schedule L
2. Schedule W
3. Schedule X
4. Schedule M
80) Erythroblastosis foetalis arises due to the incompatibility in the:
1. Lymph
2. Blood
3. Synovial fluid
4. Bile
81) A rectal suppository is used to treat a fever. This would represent what type of drug delivery?
1. Parenteral and local
2. Parenteral and systemic
3. Enteral and local
4. Enteral and systemic
82) The following prescriptions are presented at the community pharmacy where you are employed. Which prescription would cause you the greatest concern?
1. Mr Holmes is prescribed pholcodeine linctus for her dry cough. His patient medication record (PMR) indicates that he is also prescribed inhalers for asthma.
2. Miss Ahmed is prescribed pholcodeine linctus for her dry cough. Her medical history indicates that she has hypertension.
3. Mr Gupta is prescribed pholcodeine linctus for his dry cough. He tells you that he has gastro oesophageal reflux disease (GORD).
4. Mrs Vaid is prescribed pholcodeine linctus for her dry cough. Her medical history indicates that she also has chronic bronchitis.
83) The separation of prescribing and dispensing into different roles was a key stage in the evolution of healthcare. The separation came about with:
1. The formation of the Pharmaceutical Society in 1841
2. The registration of chemists and druggists in 1868
3. The National Insurance Act in 1911
4. The formation of the NHS in 1948
84) Which of the following is NOT true regarding spleen?
1. It is a part of the reticuloendothelial system
2. It is the site of destruction of red blood cells in the body
3. Removal of spleen does not affect immunity of the body
4. Splenic enlargment can occur in certain cases of blood cancer
85) Which of the following is not used as a contraceptive method?
1. Intrauterine copper devices
2. Combined oestrogen progesterone pills
3. Female condoms
4. Follicular Stimulation Hormone (FSH) pills
86) Capsules normally fall into two main categories. Which are they?
1. Hard gelatin capsules and soft gelatin capsules
2. Hard gelatin capsules and layered capsules
3. Soft gelatin capsules and compressed capsules
4. Compressed and layered capsules
87) Which of the following provides the best definition of pharmaceutics?
1. It is the study of dosage form design including associated manufacturing techniques.
2. It is the study of the effect that the body has on drugs.
3. it is the study of how drugs can be chemically synthesised.
4. It is the study of the effect that drugs have on the body.
88) Which one of the following is NOT true? Tablets are often coated:
1. To mask bitter tastes
2. To increase friability
3. To protect the drug from the external environment
4. To make swallowing easier
89) Which one of the following is NOT a concentration unit?
1. Molarity
2. Enthalpy
3. Mass per volume
4. Milliequivalent
90) Which one of the following is NOT true?
1. Hydrophobic drugs dissolve slowly
2. Hydrophobic drugs have low solubility in water
3. Hydrophobic drugs are easily wetted
4. Drugs can be hydrophilic or hydrophobic
91) Which of the following excipients may be used to limit the presence of microorganisms in a liquid formulation?
1. Sodium lauryl sulphate
2. Benzalkonium chloride
3. Purified water
4. Ascorbic acid
92) What are the protein structures called that are expressed within the cell membranes and interact with endogenous signalling molecules or some drugs to initiate an intracellular response?
1. Enzymes
2. Receptors
3. Hormones
4. Ligands
93) Which of the following is the correct definition of bioavailability?
1. Bioavailability is used to describe the fraction of the dose of drug administered that is present within the body and facilitates the desired physiological effects.
2. Bioavailability describes the proportion of the drug administered that is metabolised very quickly and thus is not available to induce a physiological effect.
3. Bioavailability describes the ability of the administered drug metabolites to cause undesirable physiological effects.
4. Bioavailability is the length of time an administered drug is present in the body and thus is available to cause a physiological effect.
94) Patients with penicillin allergies are frequently allergic to which of the following class of antibiotics?
1. Cephalosporins
2. Quinolones
3. Macrolides
4. Aminoglycosides
95) Which of these is not a reason why a knowledge of behavioural and social sciences is important to pharmacists?
1. 54 It can help to build a concordant relationship with patients
2. Knowing what people are thinking is more important than knowledge of medicines
3. It can improve adherence to medication
4. It can help us to understand patients better
96) Salbutamol is an effective treatment for asthma- which of the following statements is not true:
1. It is active at the [32-adrenorecptor
2. It can be synthesised from aspirin
3. The (R)-stereoisomer is the more active
4. It has a shorter duration of action than adrenaline
97) onversion of a carboxylic acid to an ester is known as
1. Reduction
2. Oxidation
3. Esterification
4. Polymerisation
98) Which of the following statements explains receptor affinity?
1. It is half the dose needed for maximal response.
2. It is a measure of how tightly a ligand hinds to a receptor.
3. It is the maximum response downstream of a receptor
4. It is the concentration of ligand that causes side effects.
99) The study of the biochemical and physiological effects of drugs and their mechanisms of action is known as
1. Pharmacoeconomics
2. Pharmacogenetics
3. Pharmacoepidemiology
4. Pharmacodynamics
100) A drug with narrow therapeutic window
1. Can be used over a wide range of doses
2. Has a limited possibility of side effects in higher doses
3. Has a low safety margin
4. Safer than a drug with high therapeutic window
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