Thermo Fisher Scientific Inc is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of 13 billion USD, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and Unity™ Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management.
Post : Scientist II, Protein Biology
Role : To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, and cell biology methods.
Responsibilities :
• Contribute in a fast- paced environment towards Antibody development & Validation
• Project leadership role in new antibody development programs with vast experience in experimental planning and execution to meet the program objectives.
• Lead team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research,
• Design and experimental execution, interpreting data and data presentation to the stakeholders.
• Drive ideation within teams to enable development of successful protocols for effective transfer to operation teams.
• Serve as domain expert in the field of flow cytometry, cell sorting and protein biology to provide inputs and guidance towards driving innovation and cross team collaborations.
• Knowledge of product commercialization processes from concept to launch including early feasibility, development, and validation phases.
• Support manufacturing team for technical support and quality by providing technical guidance.
Candidate Profile
• PhD with 2 to 4 years' experience, or
• Masters degree with 5 to 10 years' experience
• Min 3-4 years of Industrial experience is required
• Applicants should have a degree in a relevant life sciences field with a strong focus on sophisticated flow cytometry, cell sorting, panel design and immunology.
Nature of experience
• Strong background in flow cytometry including single cell sorting, immunophenotyping, multicolor flow cytometry and panel design, rare population analysis
• Hands-on experience with both intracellular and extracellular multi-color staining
• Understanding of cytometry data analysis techniques (e.g. population gating, compensation, etc.)
• Proficiency with flow cytometry analysis software (e.g. FlowJo, FCS Express)
• Ability to process tissue and isolate cells, particularly human/mammalian PBMCs and mouse splenocytes
• Solid understanding and hands on experience with monoclonal antibody development methods using one or more of the following technologies would be an advantage: single B cell sorting, phage display, recombinant technology
• Experience in preparing and culturing human and mouse primary immune cells
• Proficient in molecular biology workflows such as high-throughput molecular cloning, plasmid vector construction, PCRs, Restriction digestion, Ligation, Transformation, Mini and maxi preps, sequencing
• Thorough in biochemical and immunoassay workflows such as recombinant protein expression and purification, ELISA, SDS-PAGE, Western blotting, IF, IHC
• Working knowledge of fluorescence microscopy, fluorescence detection technologies is helpful
• Experience in authoring and optimizing standard operating procedures with a focus on reproducibility
• Aptitude for identifying deviations from expected outcomes, troubleshooting and suggesting alternatives
• Excellent written and verbal presentation skills
• Proven leadership skills and ability to work alongside colleagues from different backgrounds
• Ability to succeed with a moderate level of supervision and guidance
• Ability to provide technical trouble shooting to resolve scientific problems.
• Proficient in software or platforms for molecular biology and sequence analysis, MS Office and statistical software such as GraphPad Prism.
• Authorship of peer-reviewed publications with post-doctoral experience and a strong, independent understanding of standard and emerging research protocols and techniques are preferred. GLP experience is a must.
• Prior project leadership experience preferred.
Additional Information
Qualification : Masters or PhD
Experience : 3-4 years
Location : Bengaluru, Karnataka
Industry Type : Pharma/ Healthcare/ Clinical research
Functional Area : Research & Development
End Date : 25th May 2024
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