Syngene looking for MET ID Scientist

Syngene is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply. At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit.

Post : MET ID Scientist

Job Description
Core Purpose of the Role
Bioanalytical scientist with expertise in handling LCMS/MS and support ADME screening assays: InVitro assays, MET ID and large molecule analysis by LCMS and in line with business needs.

Role Accountabilities
• Optimization of test compounds and to develop high throughput, fit for purpose LC-MS/MS and HPLC-UV methods to support ADME samples analysis: Formulations analysis, solubility studies, stability studies, In vitro assays, MET ID and large molecule analysis etc.
• Perform analysis of samples generated for the screening of compounds for ADME assays and Processing of different matrices/formulation samples of PK studies with no/minimal supervision
• Excellent written and oral communication skills interacting with internal stakeholders
• Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system
• Preparation of protocols, reports and templates for responsible activities
• Instrument maintenance, scheduling calibration and maintaining documentation as per regulatory compliance and company policy
• Adhering to safety and quality policies laid by organization
• Delivery of quality data with planning, execution of bioanalytical activities within the team in agreeable timelines
• Development and implementation of high throughput, fit for purpose bioanalytical methods to support invitro ADME samples analysis
• Identification of problem and trouble shooting in quick turn-around time
• Mentoring team members to generate quality data within agreed timelines
• To perform MET ID studies and providing final quality data with interpretation
• Peptide/ large molecule bioanalysis
• Coordination with related invitro verticals to plan the bioanalysis in cassette
• Excellent written and oral communication skills interacting with internal/external stakeholders
• Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system
• Preparation of protocols, reports and templates for responsible activities
• Instrument maintenance, calibration and maintaining documentation as per regulatory requirements and company policy
• Adhering to safety and quality policies laid by organization
• Formulation analysis data review and trouble-shooting for quicker resolution

Candidate Profile
• M. Pharm in Pharmaceutical sciences/ Relevant master’s degree in pharmaceutical sciences or instrumentation
• Good communication skills
• Strong problem-solving and handling skills
• Team Player
• Ability to learn/implement new assay in ADME and Analytical
• Quality compliance skills
Behavioral Skills
• Ability to manage a team of professionals to deliver quality work within the time frame, train and coach junior scientists, inculcate good work ethics.
• Ability to work with co‐workers and outside agencies professionally and tactfully.
• Excellent verbal/written communication and ability to communicate effectively with high transparency is essential.
• Interpersonal skills with an emphasis on working in a team environment to accomplish impactful results.
Experience : Minimum 6 to 9 years of relevant industrial experience

Demonstrated Capability
• Hands-on experience in handling of LC-MS/MS systems is mandatory and experience on HRMS is advantageous
• Expertise in column selection, mobile phase selection, solvent preparations and sample processing techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction
• Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assay samples analysis.
• Basic knowledge on Large molecule and Peptides analysis using LCMS/HRMS
• Should assist/deliver the scientific presentation in departmental journal club and write official Project reports
• Should be equipped with quality policies related to data management and data integrity

Additional Information
Experience : Minimum 6 to 9 years
Qualification : M.Pharm
Job Location : Bangalore
Pay Grade : 8-I
Industry Type : Pharma/ Healthcare/ Clinical research
Job Title : Invitro ADME Bioanalyst
End Date : 10th August 2024