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Required TRANSLATIONAL SCIENTIST FOR CANCER & VIRAL VACCINES PROGRAM @ RGCB

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The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST). In 1991, recognizing its potential, the C-DEST was made a “Grant-in-Aid” institute of the Government of Kerala and renamed as Rajiv Gandhi Centre for Development of Education, Science and Technology (RGC-DEST), becoming the first institute in the country to be named after Sri Rajiv Gandhi, the young illustrious and visionary former Prime Minster of India.

Post: TRANSLATIONAL SCIENTIST FOR CANCER & VIRAL VACCINES PROGRAM (CONTRACTUAL POSITION)

Job Description
The individual will be a highly innovative well-trained scientist to lead bio-analytical development projects and activities including assay development, qualification, testing, and characterization of novel viral and cancer vaccine candidates. This individual will be actively engaged in upstream and downstream process and product development within a dynamic project team. The scientist must display strong technical knowledge, initiative and scientific commitment, and makes significant scientific and technical contributions to the research program. The scientist will have formal supervisory responsibilities, in which case the individual must create goals and development plans for direct reports, and be also responsible for teaching, guiding and mentoring.

The Group Leader's responsibilities include
1.Establishing and carrying out appropriate processes and SOPs for upstream and downstream process development support, mammalian, insect, microbial Cell Culture, protein expression and purification methods, molecular biology (DNA and RNA isolation, RT-PCR, real-time RT-PCR, qPCR, T7 runoff, transfection, cloning, etc.), protein biochemistry (protein folding, protein degradation, aggregation, etc., immunoassay: ELISA, Flow Cytometry, IHC, IFM, general and specific analytical methods (HPLC, electrophoresis, spectrophotometry, microscopy, assay development, etc.), document writing, data interpretation, presentation, statistical analysis and trending.
2.Implement knowledge and expertise to successfully execute specific aspects of projects that involve expression of specific protein molecule(s), generation of VLPs, replicon particles, recombinant viruses, primary recovery of the cell paste, inclusion bodies and specific proteins, purification of proteins, VLPs, replicon particles, participation in decision-making processes within the project team by actively engaging in scientific and technical discussions

The scientist will have relevant bio-technology/pharmaceutical development and least 5 years of relevant work experience in new product development & technology transfer in the biotechnology, diagnostic, or vaccine industry. This will be a contract position initially for 5 years and then extended on mutual agreement subject to good performance. Has considerable knowledge and expertise relevant to Vaccine Development, Immunology, Viruses/VLPs. Knowledge/expertise should be practical and focused on lab-related activities:

Education and Previous Experience
Ph.D. degree (in Biotechnology, Molecular Biology, Immunology, Biochemistry or related field.
At least 10 years of experience in pharmaceutical or biotechnology industry.
An impressive track record along record of publications in internationally recognized journals.

Pay and allowances will be in accordance with Government of India guidelines (at an equivalent of E-II or F level scientists) depending on qualifications and previous track record of the selected candidate.

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SELECTION PROCEDURE FOR SCIENTISTS
Level 1 Screening
An Institutional Screening Committee (ISC) will be determine whether the applicant meets minimum prescribed qualifications for the advertised scientist position at RGCB. Ineligible applicants without these needed minimum qualifications will be rejected and no further correspondence will be sent to them. Applications shortlisted after the Level I screening by the ISC will be sent for Level 2 screening.

Level 2 Screening
A Faculty Screening Committee (FSC) will analyze the applications forwarded to it by the ISC after Level 1 screening. Level 2 screening includes detailed review of the applicant's credentials, publications, achievements, etc. Applicants may also be invited to give a seminar at RGCB. The FSC will decide in which grade the applicant can be considered and forward such recommendations to the Scientist Selection Committee (SSC). The Chairman of the Faculty Screening Committee will be a member of the SSC.

Final Selection Procedures
The SSC will or its individual members will speak to applicants personally, go over their plans and ideas with them and understand their long-term career goals. They will also assess the applicant's value to the development of RGCB and its R&D programs. The selection committee will also hold direct discussions with the shortlisted applicants either in person or through video conferencing. The SSC will take the final decision on whether to advice the institute to make an offer to the applicant and if so which grade of scientist is to be offered. The institute will then make a final administrative decision on this.

General Conditions/ Instructions

  1. The Director, RGCB reserves right to not to fill any or all positions advertised.
  2. The candidates must be citizens of India.
  3. Merely fulfilling the requirements in the advertisement will not automatically entitle any candidate to be considered for the position. The applications received will be scrutinized and candidates who in the opinion of the institute are likely to be suitable will be shortlisted for further selection procedures. The Screening and Selection Committees will make appropriate decision on total and individual impact factors in relation to the overall application, research areas and needs of the institute. The decision of the institute in all these matters will be final. No interim enquiries/ correspondence/communication of any sort will be entertained in the matter.
  4. Persons working under the Central/State Government/Public Sector Undertakings/ Central Autonomous Bodies shall submit their applications through proper channel. They may, however, send an advance copy of the application along with enclosures as required. Those who are unable to forward their application through proper channel may submit NOC from their employer at the time of selection interview, if shortlisted. Without this NOC, the applicant will not be allowed to attend the selection procedures.
  5. Canvassing in any manner would entail disqualification of the candidature.

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