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Cell Injury
Cell injury is defined as a variety of stress, a cell encounter as a result in changes in its internal and external environment.
All cells of body have an inbuilt mechanism to deal with changes in environment to an extent.
(RCI-Reversible Cell Injury; ICI-Irreversible Cell Injury)
Sub Topics:
cell Adaption
The cellular response to cell injury depends upon followings:
1. The type of cell and tissue involved.
2. On extent and type of cell injury.
Cellular responses to injury as follows:
1. The cell may adapt to changes which are expressed morphologically and then revert back to normal after the stress is removed. (Cellular Adaptation)
2. When the stress is mild to moderate, the injured cell may recover (Reversible Cell Injury), while when the injury is persistent, the cell may die. (Irreversible Cell Injury)
3. The residual effect of reversible cell injury may persist in the cell as evidence of cell injury at sub cellular level (Sub cellular Changes) or metabolites may accumulate within cell. (Intracellular Accumulation)
In mammalian cell under normal condition, cells are dynamic structures existing in fluid environment. A cell is enclosed by cell membrane that extends internally to enclose nucleus and other organelles suspended in cytosol.
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