Pharmacognosy Articles

About Author:
Aarti Narkhede
Mahakal Institute of Pharmaceutical Studies,
Ujjain, MP
narkhede_aarti@rediffmail.com

ABSTRACT
The use of natural product has increased tremendously in a western world as well as in developing countries or in all over part of world. via this artical therapeutic potential and future prospect of Psidium guajava L. are described. Psidium guajava L. belonging to family, myrtaceae. It is a commen tree and easily found in a tropical countries or area. Traditionally it is a very popular and used from long time in a various system of medicine like, unani, Siddha, homeopathy and Ayurveda. It is used for treatment of many ailments like diarrhea, dysentery, wounds, rheumatism, lungs problems, ulcers, skin infections, vaginal discharge, epilepsy, menstrual pain, sore throat, mouth swelling, cold and cough, toothache and etc. In present time study on antipoliferitive or anticancer activities are undertaken and it is found that anticancer activity of P.Guajava has a four time greater than vincristine.

About Authors:
Awan Bharti^*1, Sweta Gautam^2
1Department of Pharmacognosy,
Shri Rawatpura Sarkar Institute of Pharmacy, Datia, M.P.
²Department of Pharmacognosy, RKDF College of Pharmacy, Bhopal
*bhartiawan@gmail.com, shwetagautam85@rediffmail

ABSTRACT
Interest in alternative medicine and plant-derived medications that affect the "mind" is growing. Anxiety affects one-eighth of the total population of the world and has become a very important area of research interest in psychopharmacology during this decade. Anxiety, a state of excessive fear, is characterized by motor tension, sympathetic hyperactivity, and apprehension and vigilance syndromes. Benzodiazepines are the major class of compounds used in anxiety and they have remained the most commonly prescribed treatment for anxiety, despite the important unwanted side effects that they produce such as sedation, muscle relaxation, ataxia, amnesia, ethanol and barbiturate potentiation and tolerance. Various types of herbal medicines have been used as anxiolytic drugs in different parts of the world. Folk medicines have particular values, for example, plants that "calm down", tranquilize, and raise mood, such as Passiflora coerulea, Valeriana officinalis, Matricaria recutita, Jatropa cilliata, Salvia guaranitica, Tilia tormentosa, and Tilia europeae. Plants have long been used to treat central nervous system (CNS) disorders.

About Authors:
Sharda roy*, vikas chandra roy, dr. R. C. Roy
Address Faculty of Pharmaceutical Sciences. Global College of Pharmacy.
Kahnpur Khui. Punjab.
*roysharda08@gmail.com

Abstract:
Mitragyna parvifolia is a medium to large size tree belonging to the family Rubiaceae. It is popularly known as Kaim and is found growing gregariously throughout the drier parts of India, Pakistan and Srilanka. The aerial parts, stem-bark and roots of the tree contain various indolic (tetrahydroalstonine, akkuamigine, hirsuteine etc) and oxindolic (mitraphylline, isomitraphylline, pteropodine, isopteropodine etc) alkaloids. Important variations in the nature and quantity of alkaloids present in different parts of the plant are visible with change in geographical locations. In addition, various parts of the tree such as fruit juice, leaves and stem bark have been used in the traditional system of medicine by the natives and tribal since times immemorial. Mitragyna parvifolia has also got diverse medicinal and therapeutic properties such as analgesic, antipyretic, anti-inflammatory, antiarthritic, anthelmentic, antioxidant etc which have been validated scientifically. In this study we have critically reviewed the pharmacognostic and chemical profile, the traditional and the scientifically validated bioactivities of the plant.

About Author:
Bandana patel
Shri Ram Institute Of Technology
Jabalpur(M.P.) 482002
Vandanapatel.mbbs@gmail.com

Abstract:
Tagetes erectus leaf  were evaluated against various gram +ve and gram–ve bacteria and fungi, ethanol extracts exhibited very satisfactory inhibitory activity. Further studies involving the isolation, characterization and purification of the chemical compounds of the plant and screening for antibacterial and antifungal may result in the development of a potent entity which will be of lower toxicity and a high therapeutic value to the mankind.

About Authors:
Nishtha mukherjee
Shri ram institute of technology
jabalpur (m.p.) 482002
Nishthamukherjee210@gmail.com

ABSTRACT: Eclipta alba offers a remarkable activities for curing of many diseases. It has wide range of chemical constituents. Clinical investigations have been done on pharmacological activities like hepatotoxicity, proliferative, diabetic, hypolipedemic etc. Eclipta alba leaves were collected and dried. Furthur aquous and ethanolic extract were prepared and evaluated for anti microbial, anxiolytic and muscle relaxant activity.

About Authors:
Anuradha Shinde
S.R.T.M. University Nanded,
Maharashtra India
anushindebiotech@yahoo.com

ABSTRACT
The present invention relates to a filamentous fungus useful for the production of heterologous polypeptides, having been modified by recombinant DNA technology in a manner by which the expression of alkaline proteases have been completely or partially inactivated. The invention also encompasses processes for the production of proteins of interest in high yields by using the fungi of the invention. The invention furthermore relates to methods for producing such fungi and DNA constructs to be used in these methods. Extracellular alkaline proteases from Neurospora crassa is produced for the commercial requirement of proteases. The purification procedure consisted of an ammonium sulfate precipitation, dialysis, and anion-exchange chromatography, and gel filtration. We found only one enzyme identical by polyacrylamide gel electrophoresis. Optimization was done with characterization of enzyme. With a pH value of 10.0 and temperature 60 c the enzyme production was increased.

About Authors:
Zubair Khalid Labu¹; AK Mohiuddin¹; M.A Bake^*2
1Department of Pharmacy, World University of Bangladesh (WUB), Dhaka-1215, Bangladesh
^*2Product Development officer, Gonoshasthaya Pharmaceuticals Ltd., Mirzanagar, Savar, Dhaka-1344.
zubairlabu@yahoo.com; *abdul.bake@yahoo.com

Abstract
Food is the major source of energy in humans as well as animals. Foods are materials taken into the body by different route which provide nourishment in the form of energy or in the building of tissues. Food contaminants are substances that make food unfit for human consumption. Examples include bacteria, toxic chemicals, carcinogens, teratogens and radioactive materials. The purpose of these studies is to find out the food contaminants which are used in different purposes available in Bangladesh and contaminants detection method. After survey we found that Dhaka is the main city where food contamination by various contaminants in higher percentage. This contamination done by manmade, industrial discharge, poisonous water etc. Government of Bangladesh taking various necessary steps to stop this contamination.

About Authors:
Himani sharma
B.pharm; mahakal institute of pharmaceutical studies,
Ujjain (m.p.); rgpv
shimani53@gmail.com

ABSTRACT
Among the several identified types of dementia, Alzheimer's dis­ease (AD) is the most common. In 1906 a German physician, Dr. Alois Alzheimer, specifically identified a collection of brain cell abnormalities as a disease which is a degenerative brain disorder. Today, this degenerative brain disorder bears his name, and when found during an autopsy, these plaques and tangles mean a definite diagnosis of Alzheimer's disease (AD).  This article provides a general idea of some main causes ofAlzheimer's disease, use of various prospects of nanotechnology herbal medicines and intended to explain the therapeutic effectiveness of various herbal medicines in the treatment of Alzheimer disease.