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July 2017

 

 

academics

 

Clinical research courses

Gilead Sciences, Inc. announced detailed 48-week results from two Phase 3 studies (Studies 1489 and 1490) evaluating the efficacy and safety of a fixed-dose combination of bictegravir (50 mg) (BIC), a novel investigational integrase strand transfer inhibitor (INSTI), and emtricitabine/tenofovir alafenamide (200/25mg) (FTC/TAF), a dual-NRTI backbone, for the treatment of HIV-1 infection in treatment-naïve adults. In the ongoing studies, BIC/FTC/TAF was found to be statistically non-inferior to regimens containing dolutegravir (50mg) (DTG) in combination with a dual-NRTI backbone. The data were presented in two late-breaker sessions [MOAB01 and TUPDB02] at the 9th IAS Conference on HIV Science (IAS 2017) in Paris.

Cyclacel Pharmaceuticals, Inc. a clinical-stage biopharmaceutical company using cell cycle, transcriptional regulation and DNA damage response biology to develop innovative, targeted medicines for cancer and other proliferative diseases, announced the closing of an underwritten public offering of units for gross proceeds of USD15.2 million, which includes the full exercise of the underwriter’s over-allotment option to purchase additional shares and warrants, prior to deducting underwriting discounts and commissions and offering expenses payable by Cyclacel. Existing and new investors participated in the offering.

The offering was comprised of Class A Units, priced at a public offering price of USD2.00 per unit, each unit consisting of one share of common stock and a seven-year warrant (each, a “warrant”) to purchase one share of common stock with an exercise price of USD2.00 per share, and Class B Units, priced at a public offering price of USD1,000 per unit, with each unit comprised of one share of preferred stock, which is convertible into 500 shares of common stock, and a warrant to purchase 500 shares of common stock, also with an exercise price of USD2.00 per share. The conversion price of the preferred stock issued in the transaction as well as the exercise price of the warrants are fixed and do not contain any variable pricing features or any price based anti-dilutive features. The preferred stock issued in this transaction includes a beneficial ownership blocker but has no dividend rights (except to the extent that dividends are also paid on the common stock), liquidation preference or other preferences over common stock, and, with certain exceptions, has no voting rights. The securities comprising the units were immediately separable and have been issued separately.

Ladenburg Thalmann & Co. Inc., a subsidiary of Ladenburg Thalmann Financial Services Inc. (NYSE MKT:LTS), acted as sole book-running manager in connection with the offering.

A total of 3,154,000 shares of common stock, 8,872 shares of preferred stock convertible into 4,436,000 shares of common stock, and total warrants to purchase 7,590,000 shares of common stock were issued in the offering, including the full exercise of the over-allotment option. If exercised in full, the warrants could result in additional net financing proceeds to Cyclacel of USD15.2 million.


The securities were offered pursuant to a registration statement on Form S-1 (File No. 333-218305) and an additional registration statement filed pursuant to Rule 462(b), which was declared effective by the United States Securities and Exchange Commission ("SEC").

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor will there be any sales of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction. A final prospectus relating to this offering has been filed by Cyclacel with the SEC. Copies of the final prospectus may be obtained at the SEC’s website at sec.gov or from Ladenburg Thalmann & Co. Inc., Prospectus Department, 277 Park Avenue, 26th Floor, New York, New York 10172, by calling (212) 409-2000.


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Trescon is honouring 50 top performing CIOs and 10 CEOs from the ever-growing Indian Pharmaceutical industry in the upcoming Pharma CIO Conclave & Awards taking place on 9 August 2017 in Mumbai.

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Recruitment for M.Pharm, M.Sc(04 posts) at IHBT | Government Jobs

Govt. of Himachal Pradesh took up initiative in early seventies to set up a CSIR lab to make prudential use of the natural resources of the region. After several levels of discussions a formal request was made by then Chief Minister of HP to Vice President, CSIR in 1982 for initiating the matter, and giving final shape to the proposal. The dream of HP government finally came true in 1983 when the foundation stone of this National lab was laid as CSIR Complex Palampur by Prof. Nurul Hasan, former Vice President of CSIR, with then Chief Minister of HP chairing the function.

Walk-in-Interview is scheduled to be held on the date(s) as mentioned below against the position(s) in the respective column for the selection of suitable candidate(s) in the following areas under the following project(s) on purely temporary basis for the duration of the projects or till completion of the projects whichever is earlier

Recruitment for Scientific Assistant / Officer at Tata Memorial Centre | Salary upto Rs 75,000

The Tata Memorial Centre (TMC) is a Comprehensive Cancer Centre with a mission to achieve the highest standards in patient care, cancer prevention, cancer research and professional development for oncology and allied disciplines. TMC is an autonomous body funded, controlled by the Department of Atomic Energy, Government of India. TMC is affiliated to Homi Bhabha National Institute (HBNI). The HBNI is a Deemed University of the Department of Atomic Energy with a mission to develop high quality postgraduate educational programs in science and technology including those related to life and health sciences. TMC invites applications from eligible candidates of Indian nationality, who are keen to pursue a career in TMC. Full time positions in various departments available in TMC are listed below.

Walk in interview for Pharmacist Urban Comunity Heleth Center

The Union Cabinet vide its decision dated 1st May 2013 has approved the launch of National Urban Health Mission (NUHM) as a Sub-mission of an over-arching National Health Mission (NHM), with National Rural Health Mission (NRHM) being the other Sub-mission of National Health Mission. Within the broad national parameters and priorities, states would have the flexibility to plan and implement state-specific action plans. The state PIP would spell out the key strategies, activities undertaken, budgetary requirements and key health outputs and outcomes.

Post : Pharmacist

Recruitment for Master’s degree in Life Science at Indian Agricultural Research Institute

The Indian Agricultural Research Institute (IARI) is the country's premier national Institute for agricultural research, education and extension. It has served the cause of science and society with distinction through first rate research, generation of appropriate technologies and development of human resources. In fact, the Green Revolution was born in the fields of IARI and our graduates constitute the core of the quality human resource in India's agricultural research and education.

Opportunity for M.Pharm to work in Department of Pharmaceutical Sciences at BIT

BIT, Mesra is a "Deemed University" under Sec. 3 of the U.G.C. Act 1956. It functions under the overall supervision, direction and control of a high power Board of Governors, comprising representatives of the Ministry of Education, Government of India, the U.G.C., the State Government, The Chancellor, the AICTE, The Hindustan Charity Trust and the Institute Faculty. Shri G.P. Birla is the Chairman of the Board of Governors. The Governor of the state of Jharkhand is the Chancellor of the Institute. The Technical Council decides the academic policy of the Institute.

Applications are invited for the post of Junior Research Fellow in Cluster Innovation Centre

With the launch of innovative schemes by MHRD and National Innovation Council, the University felt that innovation programmes be launched which should enhance creative potential of students, have innovative curriculum, are more project oriented and tailored to the need of society and industry.  Such programmes should be enabling for students to relate themselves to the real world problems in all spheres and look for innovative solution for the problems. University should work closely with all stakeholders in this endeavour.