March 2017

Vidarbha Youth Welfare Society's. Amravati is a leading group of professional institutions with a proven record of three decades in Technical Education in Vidarbha region of the state As a part of expansion programme, the Society has proposed to start a new college "Institute of Pharmacy & Research" and is looking for the self-motivated faculty members havnig passion and commitment for the great mission of teaching.

Unison Pharmaceuticals Private Limited (Formerly known as Unison Pharmaceuticals) was established in 1981 with a vision of providing quality & most affordable medicines across the nation. With more than 3 decades of medical service to the society, Unison is today one of the fastest growing company in Gujarat State.

Madhya Pradesh Professional Examination Board (MPPEB) also known as MP Vyapam has invited online applications from eligible candidates for direct recruitment of Paramedical Staffs and to fill up backlog vacancies and contractual posts with different pay bands. A Written Examination for selection of these posts will be conducted by the Board. Candidate’s age for any one of the mentioned post should not be under 18 years. Eligible aspirants having suitable qualifications may apply online for this job through the website vyapam.nic.in by 13th, March 2017. More on this topic can be seen below.

Post : Pharmacist

Siddha system of Medicine, Govt. of India, by  bifurcating the erstwhile CCRAS, formed CCRS (Central Council for Research in Siddha) with its headquarters in Chennai and six Research Institutes/Units in four states namely, Tamil Nadu (Chennai, Mettur & Palayamkottai), Puducherry (Puducherry), New Delhi and Kerala (Thiruvananthapuram). Siddha is a science of holistic health emphasising both drug and diet for human health care.

Walk in interview for various posts required in IMR research projects will be held in the above address as per details given below. Relaxation will be given to SC/ST/OBC candidates as per GOI Rules. The engagement will be purely on contract basis and no claim for continuation or regular appointment will be entertained. Applicant should bring their original certificates. No TA/DA will be paid for attending the walk-in-interview. The Asst. Director in-charge reserves all the rights to accept or reject any application without assigning any reason.

Cactus Communications—a company dedicated to the pursuit of good English. We provide editing, educational, transcription, and training services to individual and institutional clients worldwide. All our businesses are linked together by one common factor—great written English.

Teerthanker Mahaveer University is a Jain Minority State Private University established by Act No. 30 of 2008 of the Government of Uttar Pradesh and has been approved by University Grants Commission (UGC) under Section 2(f) of UGC Act, 1956. The university is located on National Highway-24 and is barely 144 Kms from National Capital, New Delhi. The University stand committed to the ideals of Lord Mahaveer i.e. Right Philosophy, Right Knowledge, and Right Conduct in all its operations and aspires to be recognized as an ultimate destination for world-class education.

Post: Professors/Associate Professors/Asstt. Professors

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ABOUT AUTHORS
Amiya Kumar Ghosh*¹, Shiladitya Palit², SaptarshiSamajdar^3
1Dept. of Pharmacy, Utkal University, Orissa
²Dept. of Pharmacy, IITBHU
³Centre for Pharmaceutical Sc. And Natural Products, Central University of Punjab
amiyaghosh94@gmail.com

ABSTRACT:
With the spread of western lifestyles, the occurrence of diabetes in the world’s population is rising. Diabetes is a complex metabolic endocrine disorder that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. It is classified into two basic forms Type I and Type II diabetes. A major goal for the treatment of type II diabetes is the enhancement of insulin secretion by pancreatic islet b-cells. The current therapeutic agents, although effective in increasing insulin secretion, are associated with undesirable side effects. Dipeptidyl peptidase IV (DPP IV) is responsible for conversion of glucose tolerance (GLP-1), into inactive form. The inhibition of DPP-IV would be beneficial in the treatment of diabetes mellitus. Improved glucose tolerance in diabetic patients was achieved with several small molecules as DPP IV inhibitors, including sitagliptin. The current study was designed to identify a suitable inhibitor agent for DPP IV. Computer-assisted molecular modeling approach has contributed to the successful discovery of several novel antidiabetic DPP IV agents.Someisoquinoline was designed computationally and screened through insilico docking studies against crystal structure of Dipeptidylpeptidase-IV (DPP-IV) ( PDB entry 2P8S )as a projected target for Type 2 Diabetes Mellitus.Insilico docking methodology using Auto Dock vina comprising a search method Genetic Lamarckian algorithm was used. Genetic Lamarckian algorithm performs an Automated Docking and has an advantage of empirical binding free energy force field that allows the prediction of binding free energies for docked ligands. In-silico evaluation shows satisfactory docking results, when compared with standard using docking. It is concluded that investigational ligands has the potential of inhibiting DPP-IV and there by further screening (invitro and invivo) studies can be carried out in order to find out optimized bioflavonoids for treating type2diabetes mellitus.

Piramal Enterprises Ltd. provides a world class integrated drug discovery services platform from our state-of-the-art research Centre in India. PDS'sa delivery model has a proven track record of providing a step change in the effectiveness of drug discovery for a range of global pharmaceuticals and biotechnology companies operating at the forefront of drug discovery. PDS understands that early and intensive evaluation of the molecules based on thorough communications and rapid decision-making will lead to a high throughput of successful drug-like compounds.

Post: Research Scientist - Analytical