December 2016

Nalanda Institute of Pharmaceutical Sciences is an AICTE approved college offering Bachelor of Pharmacy (B.Pharm) course and Unaided – Private institution affiliated to Jawaharlal Nehru Technological University, Kakinada situated at Siddharth Nagar, Kantepudi, Sattenapalli, Guntur-522438, Andhra Pradesh  This college offers B Pharmacy in India, a 4-Year Course for B Pharma degree. This pharmacy college may offer courses for Post Graduate Diploma, Diploma in Pharmacy, and D.Pharm courses, please contact respective college or affiliated university for details.

GIET School of Pharmacy offering B.Pharm, Pharm.D and M.Pharm courses approved by all India Council for Technical Education (AICTE), recognized by Pharmacy Council of India (PCI), New Delhi and affiliated to Andhra University, Visakhapatnam. GIET School of Pharmacy is situated in a sprawling 300 acres concrete campus with Wifi and state of the art learning technology and with facilities like Bank ATM, Cafeteria, Gymnasium, Clinic, Sports equipments facilities and Food courts. It is located at Rajahmundry.

Post : Assistant professor/Associate professor - 02 posts

Perrigo, headquartered in Ireland is One of the World’s leading Pharmaceuticals Manufacturers, a global healthcare supplier that develops, manufactures and distributes over-the-counter (OTC) and prescription (Rx) pharmaceuticals, nutritional products, and active pharmaceutical ingredients (API), as well as receives royalties from Multiple Sclerosis drug Tysabri®. Nearly 13,000 Perrigo employees around the world commit themselves each day to the important mission of making Quality Affordable Healthcare Products. Over 3,000 unique formulations with over  18,000 SKUs, 50 Billion Oral solid and liquid/cream doses every year.

Post: Assistant Scientist - Formulation R&D

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ABOUT AUHTOR
SUSMITA DAS*
Department of Pharmaceutical Technology, 
Jadavpur University,
West Bengal, India
*sdas53662@gmail.com

ABSTRACT:
Objectives: The aim of the present study was to develop transdermal matrix patches with a fixed ratios of polyvinylpyrrolidone (PVP) and ethylcellulose (EC), containing the drug diclofenac sodium and to perform the physicochemical, in vitro relese pattern evaluation of the prepared patches. The prospective objective was the demonstration that the system provides the delivery of drug at a controlled rate across intact skin to achieve a therapeutically effective drug level for a longer period of time from transdermal patches.
Methods: In this study, matrix-type transdermal patches containing diclofenac sodium were prepared using different ratio of polyvinylpyrrolidone (PVP) and ethylcellulose (EC) by solvent evaporation technique. The drug matrix film of PVP and EC was casted on a polyvinylalcohol backing membrane. All the prepared formulations were subjected to physical studies (moisture content, moisture uptake, and flatness), and in-vitro release kinetics and permeation studies were performed across cadaver skin using a modified diffusion cell.
Results and conclusion: Variations in drug release profiles among the formulations studied were observed. From the formulated patches FA 1, containing PVP/EC in ratio of 1:3 shows sustained release action with 38% release after 24 h and 10 µg of drug permeation accross 1 cm² of patch area. Hence, it can be reasonably concluded that diclofenac sodium can be formulated into the transdermal matrix type patches to sustain its release characteristics for manufacturing transdermal patches of diclofenac sodium