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August 2014

 

 

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A REVIEW: DETERMINATION OF ITOPRIDE HYDROCHLORIDE IN BIOLOGICAL FLUID AND PHARMACEUTICAL DOSAGE FORMS

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ABOUT AUTHORS:
Asif I Bhim*, Vineet Jain, Hasumati Raj
Shree Dhanvantary Pharmacy College,
Kim, Gujarat, India
bhimiqbal23@gmail.com

ABSTRACT:
Itopride Hydrochloride is a novel, synthesized, gastro prokinetic drug, which stimulates gastrointestinal motor activity through the synergistic effects of dopamine D2-receptor blockade and acetylcholine esterase inhibitors. Chemically, it is N-[[4-[2-(Dimethyl amino) ethoxy] phenyl] methyl]-3, 4-dimethoxy benzamide hydrochloride. Benzamide structure, amide and ether linkages in the drug molecule make it susceptible to degradation. Thus a prokinetic drug like Itopride Hydrochloride by virtue of its efficacy and tolerability could be considered as a drug of first choice and a welcome addition to the drug armamentarium for the symptomatic treatment of NUD (non-ulcer Dyspepsia) and other gastric motility disorders including functional bowel disorders. This review consists of various analytical methods for determination of Itopride Hydrochloride in various marketed pharmaceutical preparation and in biological fluids. Analytical method consists of various spectroscopic methods, chromatographic methods and other methods.

Required for Assistant Professor (IPR/Patents), Research Assistant in Gujarat Technological University

Gujarat Technological University (G.T.U) invites applications for contract based (for 6 months) Assistant Professor (IPR/Patents), Research Assistant(IPR), Research Assistant(Pharmacy). Eligibility/other details & application format may be downloaded from website: gtu.ac.in. Filled application should reach the University Office by 25-08-2014 (Except public holidays). The date of personal interview & shortlisted candidates will be declare on GTU website in recruitment section.

Post: Assistant Professor (IPR/Patents), Research Assistant

Invitation for Pharmacist in ECHS Bhuj (Kutch)

Military Station Bhuj invites application for contractual employment of medical staff/ pan medical staff/ group D staff for an Ex-servicemen contributory health scheme(ECHS) polyclinic (Type D) at military station bhuj (Kutch) gujarat as per the following details:

Post: Pharmacist

Vacancy for Junior Scientist in National Institute of Biologicals

The National Institute of Biologicals, an autonomous Institute under the Ministry of Health & Family Welfare, Government of India, is a premier Scientific Organization and a Centre of Excellence to ensure quality of vaccines and biologicals in the country.
Applications are invited for the following posts on direct recruitment basis:

Post: Jr. Scientist

Job as Editor/Product Manager in Panacea Biotec | B.Pharm, M.Pharm, MBA

Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
We offer stimulating work environment & a career that spells growth. In tune with our plans, we require young, aggressive, dynamic, high performing and result oriented professional.

Post: Editor/Product Manager

Career opportunity for Factory Manager in Shwet Biotech

Shwet Biotech Pvt. Ltd incorporated in the year 2010 and company is managed by Mr. Santosh Singh and Mrs. Anita Singh. Company’s main object is to engage in development, production and marketing of concentrated acetate hemodialysis solution, potassium free acetate hemodialysis solution and calcium free acetate hemodialysis solution. These are applicable in patients with acute or chronic renal failure, detoxification, acute intoxication and patients with calcium and lipid metabolism disorders. These products are mainly sold to hospitals which are equipped with dialysis units.

Post: Factory Manager

Opening for Corporate Quality Assurance - AM/Manager in Panacea Biotec

Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
We offer stimulating work environment & a career that spells growth. In tune with our plans, we require young, aggressive, dynamic, high performing and result oriented professional.

Post: Corporate Quality Assurance - AM/Manager

Walk in interview for Project Assistant in NIOH

The following post is to be filled up under time bound research project entitled Investigation of factors affecting in vitro fertilization” at division of Reproductive and Cytotoxicology, at National Institute of Occupational Health, Ahmedabad. The post is purely temporary, ad-hoc & contractual basis and co-terminus with the project:

Post: Project Assistant (One)

ALTERNATIVES TO THE DRAIZE EYE TEST
Vacancies in Government of Jammu and Kashmir, Services Selection Board, for Pharma graduates - 35 posts

Online application forms are invited from the eligible candidates for participating in the selection process to be followed for the State, Divisional and District cadre.