February 2014

Origo Pharmaceuticals Pvt Ltd is a leading company offering a unique range of cosmetics products in the skin-care, anti-aging and hair-care segment to its customers across India and the Middle-East. Our products are manufactured at our state-of-art facility in Bangkok, Thailand. We also offer tailored dermato-cosmetics products (contract manufacturing services) for many of the leading dermatologists/cosmetologists in India. Currently, we are headquartered in Bangalore, India having international offices in Bangkok and Dubai.

From a modest beginning in 2007, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad has now grown into a fully integrated global pharmaceutical education and research institute. The guiding philosophy of the institute, throughout, has been creation of knowledge, influencing Pharmaceutical fields that integrates globally. The objectives of imparting education, combined with creation, dissemination and application of knowledge, are being met in an integrated form, to create a synergetic impact.

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About Authors:
Hemant Maheta, MR Patel, KR Patel, MS Patel
Department of Pharmaceutics,
Shri B.M.Shah College of Pharmaceutical Education and Research,
College Campus, Modasa-383315, Gujarat, India.
hsmehta19@gmail.com

Abstract:
The purpose of writing this review on floating drug delivery systems was special focus on the principle mechanism of floatation to achieve gastric retention. Conventional oral dosage forms has short residence times & unpredictable gastric emptying time. The idea of gastric retention comes from the need to localize drugs at a specific region of gastrointestinal tract (GIT) such as stomach in the body. Many drugs get absorbed only in the upper intestinal tract, designing such molecules as once-daily formulations are exclusive for these molecules. Thus GI retention platforms had emerged. Gastroretentive drug delivery systems are designed to be retained in the stomach for a prolonged time. Gastroretentive drug delivery systems have potential for use as controlled release drug delivery system. The use of floating drug delivery system is one method to achieve prolonged gastric residence times, providing opportunity for both local & systemic drug action. Thus, gastroretention could help to provide greater availability of new products and consequently improved therapeutic activity and substantial benefits to patients. This article aims at reviewing the floating drug delivery system including types, approaches for designing the floating dosage form, advantages & disadvantages of FDDS.

Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.
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