January 2014

15 January 2014

Opening for Senior Research Fellow in Jamia Millia Islamia

Jamia Millia Islamia, an institution originally established at Aligarh in United Provinces, India in 1920 became a Central University by an act of the Indian Parliament in 1988. In Urdu language, Jamia means ‘University’, and Millia means ‘National’. The story of its growth from a small institution in the pre-independence India to a central university located in New Delhi—offering integrated education from nursery to research in specialized areas—is a saga of dedication, conviction and vision of a people who worked against all odds and saw it growing step by step. They “built up the Jamia Millia stone by stone and sacrifice by sacrifice,” said Sarojini Naidu, the nightingale of India.

Post: Senior Research Fellow

15 January 2014

Teaching Position at School of Pharmacy (SPP-SPTM) in NMIMS

The vision of NMIMS University is to define the 21st century technological and management research. Hence the goal for NMIMS University is to encourage excellence in research and publication activities. Research is a precursor to discovery and innovation. The University systems survive on the strength of research i.e. knowledge creation and dissemination system. Realities of the modern world demand interdisciplinary research or research that cuts across the traditional boundaries of discipline.

Candidates from Industry / Professions with Ph.D. degree (with First Class degree either at Bachelor’s or Master’s level) in the appropriate branch of specialization in Pharmacy and with professional work which is significant and can be recognized as equivalent to Ph.D. degree and with 15 years’ Industrial / professional experience out of which at least 5 years should be at Senior Level comparable to that of a Professor would also be eligible.

Post: Professor, Associate Professor, Assistant Professor

15 January 2014

AN INSIGHT TO IN-SITU GEL FORMING STOMACH SPECIFIC DRUG DELIVERY SYSTEM

{ DOWNLOAD AS PDF }

ABOUT AUTHORS:
Deepak Kumar*, Palak Kapoor
Shoolini University,
Solan, Himachal Pradesh
deepakkaushik354@gmail.com

ABSTRACT:
The oral delivery of drugs having narrow absorption window in the gastro-intestinal tract is limited by poor bioavailability with conventional dosage forms due to incomplete drug release and short residence time at the time of absorption. To provide controlled delivery of drugs novel drug delivery systems have been developed. Different systems have been developed to increase the gastric residence time viz. floating system, mucoadhesive, high density, expandable. Among all oral dosage forms, liquid orals are more prone to low bioavailability due to fast transit time from stomach to duodenum. Sustained/Controlled delivery can be achieved by decrease in the transit time of the dosage form. This can be augmented by an approach of liquid in-situ gelling system. These in-situ formulations are the drug delivery systems that are in sol form before administration in the body, but when administered, undergo gelation, in-situ, to form a gel. Formation of gel depends on various factors viz. temperature modulation, pH change, presence of ions, ultra-violet irradiation, from which drug releases in a sustained and controlled fashion. Different polymers which can be used for formation of in-situ gel include gellan gum, alginic acid, xyloglucan, pectin, chitosan, poly-caprolactone, poly-lactic acid, poly-lactic-co-glycolide. This article presents a detailed review of introduction, approaches to achieve in situ gelling system, polymers used, evaluation parameters, advantages of in situ gelling system.

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