December 2013

Various investigations and concerning research reports reveal that although a Pesticides Act exists to safeguard consumer interest, there is no MRL (Maximum Residue Level) in place or regulations to enforce it. Nearly every food item from rice to veggies and fruits available in the market are contaminated with poisonous pesticides, authorities caution. Pesticides and insecticides could be detrimental to people’s immune and reproductive systems. It can even lead to infertility. Developmental toxins’ in these chemicals may adversely affect the development in children. They may also act as endocrine disrupters, leading to hormonal imbalances. These chemicals are also not biodegradable(able to decompose naturally). As such, they persist for a long time and get transferred into the food chain. This means that overtime, they get deposited in the human body.

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ABOUT AUTHOR:
Amit Gangwal
Department of Pharmacognosy,
Smriti college of pharmaceutical education, Indore, Madhya Pradesh, India
gangwal.amit@gmail.com

ABSTRACT
Patents provide an incentive to the pharmaceutical industry to invest in the development of new medicines to treat diseases that are currently untreatable or incurable, and provide options when patients develop resistance to older drugs. Around the world it has been a challenge for last one or two decades to innovate concepts and mechanisms to hasten the drug development schemes/process, while augmenting dereplication ways in a full proof manner to save time, man power and financial input. High failure rate at any stage in drug development process is bothering and evoking various tools to be discussed like never before. The pharmaceutical industries world over, are in a period of crisis due to the poor number of approved drug molecules relative to the high levels of R&D investment. The drug industry is facing major scientific and strategic challenges. Moreover competition from generic giants is giving tough challenge to established products owing to end of patent rights. The concerns are further aggravated by couple of decisions announced by Indian courts (Nexavar® followed by long time pending battle of Gleevac®). These two decrees by Indian courts were not ruled in the favor of pharma giants; Bayer and Novartis respectively. Millions are dying in various part of world, owing to their inability to purchase the Elite Drugs, because of intellectual property rights. In this article various pros and cons have been discussed pertaining to generic medicines and patent fights of innovators world over.

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.

Post: Senior Regulatory Officer

Over the years Sentiss Pharma (erstwhile known Promed group) has positioned itself as the No 3 Ophthalmic Company* in Russia and has expanded its foothold in the US and European markets.
Our key competitive advantage lies in having the R&D center together with the world class manufacturing facility that has enabled us to provide end-to-end solutions from product development to marketing. Our manufacturing facility at Nalagarh (India) is EU GMP certified and TGA (Australia) approved.

Post: Manager - Quality Assurance

Indian Institute of Technology – Roorkee is among the foremost of institutes of national importance in higher technological education and in engineering, basic and applied research. Since its establishment, the Institute has played a vital role in providing the technical manpower and know-how to the country and in pursuit of research. The Institute ranks amongst the best technological institutions in the world and has contributed to all sectors of technological development. It has also been considered a trend-setter in the area of education and research in the field of science, technology, and engineering.

Applications are invited from Indian nationals only for project position(s) as per the details given below for the research project(s) under the Principal investigator (Name: Dr. Pravindra Kumar), Dept./Centre DEPARTMENT OF BIOTECHNOLOGY, Indian Institute of Technology, Roorkee.

Post: Junior Research Fellow- 1 Nos.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr. McCarrison as its first Director. It was shifted to Hyderabad in 1958.

Eligible candidates are invited to attend a WALK-IN-INTERVIEW/WRITTEN TEST at this Institute on 2^nd January, 2014 between 9.30 A.M. and 10.30 A.M. for filling up of One Senior Research Fellowship(Non-Medical) at this Institute.

Post: Senior Research Fellowship (Non-Medical) – 1 No.

HLL Lifecare Limited, a Mini Ratna Central Public Sector Enterprise under the Ministry of Health & Family Welfare, Govt. of India is a global provider of high quality healthcare products & services. With state-of-the-art manufacturing facilities spanning across India, HLL is diversifying into vaccine manufacturing, lifecare services, sanitary napkins besides engaging in procurement consultancy, healthcare infrastructure development and facility management.

The International SIGNALIFE PhD program of the University of Nice-Sophia Antipolis is currently accepting applications for twenty 3-year PhD positions, which will start in September 2014.

The Labex (Laboratory of Excellence) SIGNALIFE is a collaborative research program in Life Sciences at the University of Nice Sophia Antipolis financed by the Excellence Initiative of the French Ministry of Research. SIGNALIFE involves the leading research laboratories of the area and supports 49 top-level research teams grouped around five major topics relating to cell signaling:
1 - Cellular architecture of signaling pathways
2 – Plasticity and Signaling
3 – Stress Signaling
4 – Signaling in aging and disease progression
5 – New principles in signaling and applications

Successful candidates will enroll in the Graduate School of the University of Nice Sophia Antipolis (Life Sciences and Health Doctoral School). This University is a major interdisciplinary campus with over 25 000 students on the French Riviera in the South of France and has state-of-the-art facilities for biomedical and basic research.