November 2013

The history of the IIT system dates back to 1946 when a committee was set up by Hon'ble Sir Jogendra Singh, Member of the Viceroy's Executive Council, Department of Education, Health and Agriculture to consider the setting up of Higher Technical Institutions for post war industrial development in India. The 22 member committee headed by Sri N.R.Sarkar, in its report, recommended the establishment of four Higher Technical Institutions in the Eastern, Western, Northern and Southern regions, possibly on the lines of the Massachusetts Institute of Technology, USA, with a number of secondary institutions affiliated to it.

Post: Research Associate

Central Council For Research In Ayurvedic Sciences- Ayurveda Regional Research Institute, Jammu invited applications for filling up one post of Lab Technician. Details are as follows:

Post: Laboratory Technician

Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi under the aegis of Defence Research and Development Organisation (DRDO), is engaged in research and developmental work in radiation sciences. INMAS is looking for meritorious young researchers for pursuing research in the frontier areas at INMAS. The Institute invites applications from young and meritorious Indian nationals who are creative, have passion and desire to pursue R&D in frontier areas. INMAS possesses ambience of a research cum academic institute coupled with an advanced R&D infrastructure in a mission mode. It provides the best infrastructure, motivation and personality development prospects for talented students, dreaming of unparalleled success in their professional endeavors. INMAS provides state of the art research facilities for undertaking pioneering research with defence applications.

Post: Junior Research Fellow

The National Dairy Research Institute as country's premier Dairy Research institution has developed considerable expertise over the last five decades in different areas of Dairy Production, Processing, Management and Human Resource Development. Information generated at the Institute and the services offered have contributed to the growth of Dairy Industry as a whole and well-being of millions of milk producers and consumers of milk and milk products.

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About Authors:
Arvind Negi¹*, Balraj Singh Gill^2
1Centre for Chemical and Pharmaceutical Sciences, Central University of Punjab, Bathinda- 151001
²Centre for Biosciences, Central University of Punjab, Bathinda-151001
*arvindnegi2301@gmail.com

Abstract
Stereochemistry of clinical agents play a key role in their success to become drugs. Tautomerism is a structural isomerism, playing a key role in the orientation of organic compounds and also found significant in distinctive base pairing in nucleic acids. Keto-enol form usually occurs and found prominently among different types of tautomers. The enol form ionizes in the physiological solution into enolate and alter the biological activity. So, how this enolate form brings modification in pharmacokinetics and pharmacodynamics of a drug is very important and quite interesting to know. As this form is ionic in nature so it increases the interaction with the concerning receptors, enzymes, ion channels or functional proteins. In this review we cover and compile success, role and the significance of the enolate form of clinical agents which succeed to become drugs!

West Bengal State Electricity Distribution Company Limited (WBSEDCL), a wholly-owned profit-making and professionally managed Government of West Bengal Enterprise, engaged in the business of Power Distribution and Hydel Power Generation in major parts of the State of West Bengal with Customer Base exceeding 1.25 crore, Employee Strength of around 17,000 and Annual Turnover of Rs. 14,000 crore invites applications from Indian Nationals to fill up the following vacant posts immediately:

U.N. Mehta Institute of Cardiology and Research Center (UNMICRC) is a Grant-in-aid cardiac institute promoted by Government of Gujarat in Ahmadabad, Gujarat. The institute is affiliated to B J Medical College, Civil Hospital Campus (Medicity), Asarwa which is a Government Medical College.

For polyclinic sector 8 jind invites applications for the following positions. Application can be obtained on dated 07.11.2013 to 21.11.2013 from Jind civil surgeon's office and the last date for submission of application will 22/11/2013. All information about the selection process to fill the posts and information available with applications. Application fees will be 100 rupees.