August 2012

A state level nodal centre for Inter Disciplinary Studies has been set up in Mahatma Gandhi University, Kottayam, Kerala to impart a high quality scientific education to the youth of India today – the program is revolutionary insofar as it seeks to create scientists who also have a deep appreciation of humanities.

Madras Medical Mission is an organization inspired by the missionary zeal of Bishop Zachariah Mar Dionysius, Metropolitan of the Madras Diocese of the Orthodox Church of India.

J. B. Chemicals & Pharmaceuticals Ltd. (JBCPL), known to many as Unique Pharmaceutical Laboratories is one of India's leading global pharmaceutical companies. The company manufactures and markets a wide range of pharmaceutical formulations.

About Authors:
Borse V. G.*, Birajdar A. S., Datal A. A.
K. T. Patil College of Pharmacy,
Osmanabad-413501, Maharashtra, India.
*vishalgborse@gmail.com

ABSTRACT :
The objective of this study is to enhance dissolution rate of practically insoluble drug olanzapine, using surface solid dispersion technique. Olanzapine is classified as a thiobenzodiazepine atypical antipsychotic drug used in the treatment of schizophrenia. Surface solid dispersion technique is used to prepare solid dispersion of olanzapine using Crospovidone as carrier. Surface solid dispersion were characterised by saturation solubility studies, drug content and in- vitro dissolution studies. Solubility studies revealed a marked increase in the solubility of olanzapine with an increase in Crospovidone concentration. The best dispersion was selected based on saturation study and release study and evaluated for solid state characterization techniques Differential scanning calorimetry, FT-IR spectroscopy study. The results from DSC and IR indicated that there was no interaction between drug and carriers. Surface solid dispersion of olanzapine shows increase in aqueous solubility 4.42 fold than pure drug. SSD with Crospovidone in 1:9 ratio give highest drug release i.e. 88.87%.Surface solid dispersion is successful technique to improved drug dissolution of olanzapine with the carrier Crospovidone.

About Authors:
Vivek Chourasia*, Hemant Nagar, H.S. Chandel, Anindya Goswami
Truba Institute of Pharmacy,
Karond Gandhinagar Bypass
Bhopal (M.P.)-India
*vickyc.chourasia@gmail.com

ABSTRACT
Ficus religiosawas investigated for its possible protective effect against paracetamol and CCl₄-induced hepatic damage. IV administration of a sub-lethal dose of paracetamol (500 mg/kg) produced liver damage in rats as manifested by the rise in serum level of transaminases (AST and ALT). Ttreatment of rats with Ficus religiosa (200 mg/kg) prevented the paracetamol-induced rise in serum enzymes. The hepatotoxic dose of CCl₄ (1.5 ml/kg; orally) also raised the serum AST and ALT levels. The same dose of Ficus religiosa (200 mg/kg) was able to prevent the CCl₄-induced rise in serum enzymes. These results indicate that Ficus religiosa possesses hepatoprotective activity.

Applications are invited from Indian citizens (Male & Female) for filling up the following vacancies of Group-B & C Non-Gazetted (Combatised), Para Medical Staff in Sashastra Seema Bal. They will be governed under SSB Act and Rules applicable to other members of the Force and other Rules applicable from time to time.

PAREXEL International is a growing, fast-paced, global Clinical Research Organization (CRO) that has helped bring to market 49 of the top 50 selling pharmaceuticals. In fact, we have worked with all 10 of the world's top 10 pharmaceutical companies.

Baba Farid University of Health Sciences was established under an Act passed by the Legislature of the State of Punjab in July, 1998.