May 2012

Syngene International is one of India’s premier contract research and manufacturing organizations in providing customized service. Our services encompasses all across discovery chain: early stage discovery, process development, cGMP manufacturing and formulation development both in the small molecule and novel biologics area.

Quality healthcare and Apollo have become synonymous in the Indian subcontinent, a fact reiterated by global healthcare experts and international accreditation bodies. Committed to bring world class health care within the reach of every individual, Apollo Hospitals Group has joined hands with Munich Health, a world leader in the field of health insurance.

Shri Ram Murti Smarak College of Engineering & Technology, Bareilly & Lucknow are the self financed institutes managed and run by SRMS Trust. It is founded in 1996 and the college has demonstrated perennial evidence of merit and quality by achieving a respectable position among all parallel private and govt. colleges of UP Technical University.

About Authors:
Arpit Sharma
School of Pharmaceutical Sciences, Shoolini University
Solan, H.P. India
asarpitsharma1@gmail.com

Abstract
The gastro retentive drug delivery system is a novel approach for the drugs having narrow absorption window in the gastrointestinal tract and has poor absorption. Gastro retentive drug delivery system mainly prolongs the gastric emptying time, thereby targeting site-specific drug release. Several techniques such as floating drug delivery system, low density system, raft system, mucoadhesive system, high density system, super porous hydro gel and magnetic system, have been employed. The physiological problems like short gastric residence time and unpredictable gastric emptying time were overcome with the use of floating dosage forms which provide opportunity for both local and systemic effect. Floating drug delivery system enable prolonged and continuous input of the drug to the upper part of the gastro retentional tract and improve the bioavailability of medication that is characterized by a narrow absorption window. The present review addresses briefly about the floating drug delivery system.

Flamingo Pharmaceuticals Ltd. is a quality driven pharmaceutical company with an experience of over two decades in global markets, exporting to 52 countries and having Rs.200 crores+ turnover. Flamingo has WHO-GMP/UK MHRA certified 100% EOU unit.