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Caprylhydroxamic acid (KOPSYM)- Dual active for Cosmetics

 

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Caprylhydroxamic acid - Dual active for Cosmetics

Vinay KumarVinay Kumar Singh.  
Head-Formulation
Kumar Organic Products Research Centre Pvt. Ltd.,
Bengaluru 
Email : formulation_krc@kopresearchcentre.net

Caprylhydroxamic acid is a synthetic chelating agent that helps protect cosmetic formulas from destabilizing metal ions. It also works as a preservative, having the ability to prevent mold growth in water-based formulas. This ingredient has great flexibility since it works in all types of cosmetic formulas, including waterless (anhydrous) and its efficacy is not pH-dependent. It is sometimes combined with humectants such as glycerin or propanediol to support aesthetics or a more conventional, broad-spectrum preservative system. It's a gentle preservative that helps ensure product safety and longevity. Preservatives are especially difficult to formulate because they have to be strong enough to kill bacteria and microbial growth, but they also can't impact the effectiveness of other ingredients,which it complies.

Recommended usage levels of caprylhydroxamic acid go from 0.05–0.25% in leave-on and rinse-off products. It is a chelating agent that helps to preserve cosmetic products by neutralizing the metal ions (especially iron) in the formula (that usually come from water). Its special thing is that it also acts as a biostatic and fungistatic agent and remains active even at high pH.

The Caprylhydroxamic Acid in Skincare Market is witnessing steady growth due to increasing consumer awareness. Caprylhydroxamic acid is approved as safe for use by regulatory bodies like the FDA and is considered a more sustainable and eco-friendly alternative to traditional preservatives.


Caprylhydroxamic acid (KOPSYM) is a key ingredient used in the skincare industry due to its antimicrobial and preservative properties. The competitive landscape of CHA in the skincare market includes various players, some of which are Yantai Aurora Chemical, Beijing THTD Pharmaceutical, Nantong Prime Chemical, Daedal Industrial, Hangzhou Lingeba Technology, Zley Holdings, Hunan Hecheng Pharmaceutical Chemical, Novaphene, Sichuan Nanbu Honest and Creditable Science-tech, Puracy, INCIDDecoder, INOLEX, Carbone Scientific, Yolne, Kumar Organic and Aladdin. The KOPSYM market in skincare is highly competitive, with several key players vying forMarket share. These companies have a significant presence in the industry and have experienced various degrees of market growth.

KOPSYM has gained significant attention in the hair care industry due to its ability to inhibit the growth of harmful bacteria and fungi on the scalp, promoting a healthier environment for hair growth.


Caprylhydroxamic acid plays a crucial role in combating grey hair and hair loss.
By maintaining a clean and balanced scalp, it helps prevent the buildup of harmful microorganisms that can lead to scalp conditions such as dandruff and fungal infections.

Moreover, KOPSYM 's antimicrobial properties contribute to a healthier hair follicle environment, supporting optimal hair growth and minimizing hair loss.

Research studies have investigated the effectiveness of caprylhydroxamic acid in promoting hair regrowth.
These studies have demonstrated that KOPSYM, with its antimicrobial properties, helps create a healthy scalp environment by inhibiting the growth of harmful microorganisms.

This clean scalp environment is conducive to optimal hair growth. Additionally, the molecular properties of KOPSYM have shown potential in enhancing hair follicle health and vitality, leading to improved hair thickness and reduced hair loss.
While more research is needed to fully understand the extent of its benefits, the current scientific evidence suggests that KOPSYM can play a valuable role in supporting hair regrowth.

Benefits of Caprylhydroxamic Acid
Antimicrobial Activity
KOPSYM effectively inhibits the growth of bacteria and fungi, reducing the risk of scalp infections and associated hair loss.

Scalp Health
By creating an unfavorable environment for harmful microorganisms, KOPSYM helps maintain a clean and balanced scalp,promoting healthier hair growth.

Hair Loss Prevention
The antimicrobial properties of caprylhydroxamic acid help prevent hair loss caused by scalp infections, contributing to thicker, fuller hair.

Anti-Gray Hair Effects
While KOPSYM primarily focuses on scalp health, it indirectly aids in preventing premature graying by maintaining an optimal environment for hair follicles.
Caprylhydroxamic acid is primarily available in cosmetic formulations, including shampoos, conditioners, serums, and leave-in treatments.

These products incorporate KOPSYM as an active ingredient to deliver its beneficial properties to the scalp and hair.
KOPSYM is often used in combination with other ingredients to enhance its efficacy and provide a well-rounded hair care solution.
When seeking products containing KOPSYM, carefully review the product labels or consult with a hair care professional to identify the specific form and concentration of KOPSYM used in the formulation.

The timeframe for visible results with caprylhydroxamic acid can vary from person to person.
Consistency is key when using KOPSYM-containing products. It is recommended to use the products as directed for a sustained period to allow sufficient time for theKOPSYM to have an impact on the scalp environment and hair follicles. In general, noticeable improvements may be observed after several weeks or months of regular use.
However, it's important to keep in mind that hair growth is a gradual process and results can be influenced by individual factors such as hair growth cycle and overall scalp health.

Patience and persistence are essential when incorporating KOPSYM into your hair care routine.
According to 2019 FDA VCRP data and Council survey results, Caprylhydroxamic Acid is reported to be used in 227 formulations at maximum leave-on and rinse-off concentrations of 0.25% and 0.3%, respectively. 

It is used in products applied near the eye at up to 0.2%, in lipsticks (concentration of use data not reported), in formulations that come into contact with mucous membranes at up to 0.3%, and in baby lotions, oils, and creams at up to 0.15%.
KOPSYM and Medium Chain Terminal Diols (MCTDs) are an important class of multifunctional ingredients that are known to control microbial growth in cosmetic formulations. These combinations are optimized for use in a variety of formulation types, meeting specific formulation design and production criteria, including 100% natural combinations, high water solubility, cold process ability, and a variety of other parameters.

So Cetylhydroxamic acid is not only going to act against microbes but also serves its role as Chelating agent and has its application in various cosmetics . This is widely used preservative in various Cosmetics across product lines.