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Shri Rawatpura Sarkar Institute of Pharmacy

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Clinical research courses

  • A REVIEW: PLANTS AND HERBS USED IN ANXIETY

    About Authors:
    Awan Bharti*1, Sweta Gautam2
    1Department of Pharmacognosy,
    Shri Rawatpura Sarkar Institute of Pharmacy, Datia, M.P.
    2Department of Pharmacognosy, RKDF College of Pharmacy, Bhopal
    *bhartiawan@gmail.com, shwetagautam85@rediffmail

    ABSTRACT
    Interest in alternative medicine and plant-derived medications that affect the "mind" is growing. Anxiety affects one-eighth of the total population of the world and has become a very important area of research interest in psychopharmacology during this decade. Anxiety, a state of excessive fear, is characterized by motor tension, sympathetic hyperactivity, and apprehension and vigilance syndromes. Benzodiazepines are the major class of compounds used in anxiety and they have remained the most commonly prescribed treatment for anxiety, despite the important unwanted side effects that they produce such as sedation, muscle relaxation, ataxia, amnesia, ethanol and barbiturate potentiation and tolerance. Various types of herbal medicines have been used as anxiolytic drugs in different parts of the world. Folk medicines have particular values, for example, plants that "calm down", tranquilize, and raise mood, such as Passiflora coerulea, Valeriana officinalis, Matricaria recutita, Jatropa cilliata, Salvia guaranitica, Tilia tormentosa, and Tilia europeae. Plants have long been used to treat central nervous system (CNS) disorders.

  • PHARMACOGNOSTIC INVESTIGATION OF ELAEOCARPUS GANITRUS Roxb. LEAF AND SEED

    About Authors:
    Awan Bharti
    Department of Pharmacognosy,
    Shri Rawatpura Sarkar Institute of Pharmacy,
    Datia, M.P.
    bhartiawan@gmail.com

    ABSTRACT
    Elaeocarpus ganitrus Roxb. (Family: Elaeocarpaceae) commonly known as Rudraksha. Rudraksha beads, the holy beads scientifically called as Elaeocarpus Ganitrus. It possesses good medicinal value and with religious, medicinal and spiritual significances. Present investigation deals with macroscopic, microscopic. Microscopic studies revealed the presence of cuticle, epidermis, collenchyma, vascular bundle, xylem and phloem, hard endocarp, seeds with membranous seed coat.

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  • A REVIEW ON ANTIMALARIAL AGENTS

    About Authors:
    Gunjan Kalyani*1, Vishal S. Deshmukh1, Yogesh Vaishnav1
    1Shri Rawatpura Sarkar Institute of Pharmacy,
    Kumhari-490 042, Chhattisgarh
    kalyani.gunjan@yahoo.in, rvg_54767@yahoo.co.in*

    ABSTRACT
    Malaria caused mostly by P. falciparum and P. vivax, remains one of the most important infectious diseases in the world. The numbers of antimalarial drugs in use are very small. Drug toxicity must be acceptable to patients and should cause less harm than the disease itself. Assessment of hazard and risk varies throughout drug development as more persons are exposed for longer periods of time and more nonclinical information on the hazard is collected and evaluated. Cancer risk for human pharmaceuticals is important because drugs are taken at pharmacologically active doses and often on a chronic basis. Epidemiologic studies on patient populations have limited value because of the long latency period for most cancers and because these studies lack sensitivity. Besides the mutagenicity and genotoxicity testing of antimalarial drugs as a part of pre-clinical trials, there are several literatures confirming the mutagenicity and genotoxicity of marketed antimalarial drugs. Genetic abnormalities may also play a part in the incidence and severity of adverse reactions to drugs. In this paper, a comprehensive review of literature pertaining to the mutagenic and genotoxic properties of some commonly used antimalarial drugs is presented.

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