Review Articles

About Authors:
Jeevan Sharma¹*, Davidson Rajesh^2
1B.Pharmacy, JSS college of pharmacy Ooty
²Regional manager, Natco Pharma litmited, Chennai
*jeevan.pharma@yahoo.com

ABSTRACTS:
Attrition refers to the reduction in staff and employees in a company through normal means, such as retirement and resignation. The primary focus of this  article is to present the high rate of attrition seen in the pharmaceutical marketing  industry , its causes and controlling strategy for  retentions of pharma sales representatives. Though  attrition is a natural phenomena in all industries  , Indian Pharma marketing industries is worst plagued by It. After IT and BPO , pharma  marketing industries experience  the greatest rate of employee leaving the company for various reasons. While   global pharma  marketing attrition rate  is  10-12%  per annum, the rate of employees who leave  the organization in India is 25 -30 %.  The attrition is more prevalent in the middle and junior management level.

About Authors:Niroj Shrestha*, D. Nagasamy Venkatesh**, Jeevan Sharma
J. S. S. College of Pharmacy, Ooty, Tamilnadu, India
*Final Year B.Pharmacy Student.
**For correspondence:
Department of Pharmaceutics
J. S. S. College of Pharmacy,
(A constituent college of JSS University, Mysore)
Ooty – 643 001.
Tamil Nadu, India.

Reference ID: PHARMATUTOR-ART-1068

Abstract
Transdermal drug delivery system (TDDS) has emerged as a potential novel drug delivery system in the last 30 years to improve the therapeutic efficacy and safety, maintain steady state plasma level of drugs and overcome significant drawbacks of the conventional oral dosage forms and parenteral preparations. TDDS is ideally suited for diseases that demand chronic treatment with frequent dosing. This review deals with a brief insight on the formulation aspects, the physical and chemical enhancers being explored to enhance the transdermal delivery of drugs across the stratum corneum, the evaluation parameters (physicochemical, in vitro, in vivo studies) and therapeutic applications of TDDS.

About Authors: Rajan Sharma Bhattarai*, D.Nagasamy Venkatesh**, Ayush Shrestha
*Final Year B.Pharmacy Student.
**For correspondence
Department of Pharmaceutics
JSS College of Pharmacy, (A constituent college of JSS University, Mysore)
Ooty – 643 001, Tamil Nadu.

About Author: Amit Surani,
Dept. of Quality Assurance,
M.Pharm, Maliba College of Pharmacy, Surat
Gujarat Technical University

ABSTRACT
According to FDA, Process Analytical Technology (PAT) is a system for designing, analyzing, and controlling manufacturing process through timely measurements of critical quality and performance attributes of raw materials, in-process materials and processes with the goal of ensuring final product quality.
PAT involves the use of different technologies and tools to build quality into the products. Effective PAT implementation is based on detailed, science-based understanding of the physical, chemical and mechanical properties of all elements of the proposed drug product.
Pharmaceutical companies face many challenges while implementing PAT into their new and pre-existing manufacturing processes. This article discusses the challenges encountered by manufacturers and the benefits they can reap by successful implementation of PAT.