Maharastra

Karnataka Antibiotics and Pharmaceuticals Limited, KAPL Bengaluru is a Government of India Enterprise. Karnataka Antibiotics and Pharmaceuticals Limited is a Joint Sector Company of Government of India with shareholding from Government of Karnataka through Karnataka State Industrial Infrastructure Development Corporation KSIIDC. From a modest beginning in 1984, KAPL has grown exponentially in the areas of manufacturing and marketing of various life saving and essential drugs.

Karnataka Antibiotics and Pharmaceuticals Limited, KAPL Bengaluru is a Government of India Enterprise. Karnataka Antibiotics and Pharmaceuticals Limited is a Joint Sector Company of Government of India with shareholding from Government of Karnataka through Karnataka State Industrial Infrastructure Development Corporation KSIIDC. From a modest beginning in 1984, KAPL has grown exponentially in the areas of manufacturing and marketing of various life saving and essential drugs.

Lupin Pharmaceuticals, Inc. is the U.S. wholly owned subsidiary of Lupin Limited, which is among the top six pharmaceutical companies in India. Through our sales and marketing headquarters in Baltimore, MD, Lupin Pharmaceuticals, Inc. is dedicated to delivering high-quality, branded and generic medications trusted by healthcare professionals and patients across geographies.

About Authors
Narsinh N. Potdar*, Pranita P. Kore, Rishikesh V. Antre
Department of Pharmaceutical Chemistry,
JSPM’s Charak College of Pharmacy and Research, Wagholi,
Pune-Nagar Road, Pune-412 207 (India)
*narsinh_potdar@rediffmail.com

Abstract
Three new simple, economic spectrophotometric methods were developed for quantitative estimation of Rosuvastatin Calcium in bulk formulation. First method includes determination of Rosuvastatin Calcium at absorption maxima 252 nm, second method applied was area under curve for analysis of Rosuvastatin Calcium in the wavelength range of 247-257 nm and third method was first order derivative. Beer law obeyed in the concentration range of 5-35 μg/ml for all three methods. The correlation coefficients were found to be 0.974, 0.982 and 0.982by absorption maxima, area under curve and first order derivative spectra. Results of analysis were validated statistically and by performing recovery studies. The mean percent recoveries were found satisfactory for all three methods. The percentage label claim was found in the range of 100.28% to 101.01% .The proposed method was validated statistically and recovery studies.