About Authors:
Mukesh Bansal1*, Indrajeet Singhvi2, Santosh Gupta2
1Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P., India.
2Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India.
*bansalpharma1987@gmail.com
Abstract:
Object:
To investigate the effect of embelin on anxiety was studied by using standard test such as Elevated zero-maze test and Novelty induced suppressed feeding latency test in a dose dependent manner.
Material & methods:
This portion include extraction and isolation of embelin, animals were obtained from the animal house IMS, BHU, Varanasi, India, and methods for anxiety were Elevated zero-maze test and Novelty induced suppressed feeding latency test.
Result & conclusion:
The anxiolytic activity was found at 20mg/kg. The observed anxiolytic effect of this compound seems to be regulated through monoaminergic system in the brain and the activity was comparable to diazepam.