Research News

Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don’t make it that far. A new study shows how this Trojan Horse strategy works better by exploiting calcium differences outside and inside cells.

Patients with diabetes have an increased risk of complications after stent implantation, according to a study from Karolinska Institutet in Sweden published in Diabetes Care. The study, which includes over 160,000 patients, emphasises the importance of tailoring treatment strategies for this specific patient group.

In a breakthrough that reshapes our understanding of how the body manages fat, researchers have discovered that a well-known fat-burning enzyme, Hormone-Sensitive Lipase (HSL), has a second, unexpected job—acting inside the cell nucleus to regulate how fat cells grow, store energy, and function.

Scientists have uncovered a previously unknown function of the enzyme OTULIN in regulating the production of tau, the protein that aggregates in neurodegenerative diseases such as Alzheimers.

A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.

More than 1 million cervical cancer deaths have been prevented, and an estimated 86 million girls are now protected against the leading cause of cervical cancer, thanks to a concerted three-year effort by Gavi, the Vaccine Alliance and lower-income countries.

Novartis has announced compelling Phase III results for GanLum (ganaplacide/lumefantrine, KLU156), a next-generation antimalarial developed with Medicines for Malaria Venture (MMV). The combination therapy achieved a 97.4% PCR-corrected cure rate in the KALUMA study marking a major advancement in malaria treatment amid rising drug resistance across Africa.

A new Advocacy Paper, developed by leading nephrology experts of the country, outlines a roadmap to scale peritoneal dialysis - a simple, home-based treatment for kidney failure across India, ensuring equitable access to treatment for kidney failure, especially for rural and marginalised communities.