Neurodegeneration in Myelin Disease : No Myelin is Better than Bad Myelin
Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins. It enables rapid conduction of electrical signals and supports neuronal integrity and function. In the central nervous system, myelin is formed by specialized glial cells called oligodendrocytes. Myelinated fiber tracts are particularly vulnerable to various pathogenic processes and myelin diseases are often associated with chronic inflammation of the nervous system.