Dendrimers:-A Carrier for oral drug delivery system
About Author
Manish kumar
Hindu College Of Pharmacy, Sonipat
*maggarwal0007@gmail.com
Abstract:
Dendrimers are perfect monodisperse macromolecules(poloymers) with regular and highly branched 3-D structure. Dendrimers have often been referred to as the “Polymer of the 21st century. They are characterized by branch upon branch architecture which are completely different from traditional Polymers. Exceptional feature of a dendrimer includes a high degree of structural symmetry, a density gradient displaying an intra-molecular minimum value and a well defined number of terminal groups. Dendrimers are normally used as carriers for drug delivery especially for oral, ocular and transdermal delivery. Oral drug delivery system are very important to the field of medicine, since most of the common illness are treated via oral route. Encapsulation and conjugation of drug with dendrimers have shown immerse employment for delivery of hydrophobic and labile drugs. Anticancer and antihypertensive drugs are most promising candidates for oral route using dendrimer as carrier. Dendrimers drug delivery system are therefore increasingly viewed as an advantageous for bioactive like drugs and gene. Although dendrimer drug delivery requires attention to certain manufacturing and biological consideration to be successful.
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