Aurangabad

ABOUT AUTHORS:
MHG Dehgan, Satapathy Asis Amitav*
Y.B.Chavan College of Pharmacy,
Dr. Rafiq Zakaria Campus,
Auranagbad-431001 (MS),
*asish.apharma@gmail.com

ABSTRACT
Nasal route for the administration of drugs is used as an alternative route for the systemic availability of drugs restricted to intravenous administration. This is due to the large surface area, porous endothelial membrane, high total blood flow, the avoidance of first-pass metabolism, and ready accessibility. The nasal administration of drugs, including many biotechnological compounds like hormones, vaccines, peptide and protein drugs to give enhanced bioavailability. Many drug delivery methods for nasal availability of liquid, semisolid and solid formulation are investigated to avail the drugs to treat most CNS diseases (i.e., Parkinson’s disease, Alzheimer’s disease, Migraine attack) because it requires rapid and/or specific targeted delivery of drugs to the brain.
In this review we discuss some factors affecting nasal absorption, bio-availability barriers, and strategies to improve nasal absorption, new developments in nasal dosage form design and applications of nasal drug delivery system and the effects of microspheres, liposomes and other bioadhesive drug delivery systems on nasal drug absorption.

Ultra Beauty Care Pvt. Ltd., is a leading cosmetics manufacturing company based in Aurangabad (Maharashtra) with a state of the art manufacturing plant designed as per the Schedule M of GMP.
The company currently manufactures cosmetics on Loan License basis for leading brands. UBCPL is also involved in development of products to be offered to our exports clients on a regular basis in Europe & Africa.

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Several specialised therapeutic divisions and promising new products have been launched and many more are in the pipeline.

DKT is a leading Social Marketing Organization established in 1992. It is affiliated of DKT International USA which runs social marketing programs in 13 countries of Asia, Africa & Latin America.

Post: Medical Representative

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Alembic Limited, with an established presence in the Indian pharma  industry has a proud, historical track record going back one hundred years. With a turnover in excess of Rs1000 crores today, Alembic Limited is one of India’s leading integrated pharmaceutical companies.

Alembic Limited, with an established presence in the Indian pharma  industry has a proud, historical track record going back one hundred years. With a turnover in excess of Rs1000 crores today, Alembic Limited is one of India’s leading integrated pharmaceutical companies.