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  • New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy
    15 February 2025

    New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy

    A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. Researchers at Oregon Health & Science University have developed a test called PAC-MANN, the abbreviation for protease activity-based assay using a magnetic nanosensor which uses a small blood sample to detect changes in protease activity a key indicator of pancreatic ductal adenocarcinoma, or PDAC, the most common and deadly form of pancreatic cancer.
  • 15 February 2025
    Diabetes Can Drive the Evolution of Antibiotic Resistance

    Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to evolve and spread.

    Staphylococcus aureus is a leading cause of antibiotic resistance associated infections and deaths. It is also the most prevalent bacterial infection among those with diabetes mellitus, a chronic condition that affects blood sugar control and reduces the body’s ability to fight infections.

  • 7 February 2025
    80M Euro EU-funded Projects Launch Unprecedented Collaboration to Address the Obesity Crisis in Europe
    Over the past decades, obesity has reached epidemic proportions, now affecting more than 1 billion people worldwide. Childhood obesity, in particular, is rising at an alarming rate. According to the World Obesity Federation, the number of children with obesity is expected to double between 2020 and 2035. Obesity carries serious health consequences, strains national healthcare systems, and reduces overall quality of life.
  • 7 February 2025
    The two proteins involved in Alzheimer’s disease affect brain circuits differently
    A study using a new animal model of Alzheimers disease suggests a potential breakthrough in treatment strategies. Current therapies mainly focus on blocking just one of the toxic proteins associated with the disease, but this discovery could pave the way for more comprehensive approaches.
  • 3 February 2025
    Harnessing Generative AI to Treat Undruggable Diseases
    Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins. Inspired by OpenAI’s image generation model, their new algorithm can rapidly prioritize peptides for experimental testing.
  • 3 February 2025
    New Case Western Reserve University study identifies key protein’s role in psoriasis

    Psoriasis, a painful and uncomfortable inflammatory skin condition that affects millions worldwide, flares up from the activity of disease- and infection-protecting immune cells.

    In a new study, researchers at Case Western Reserve University School of Medicine have determined that a protein called NF-kB c-Rel can intensify the condition’s symptoms when activated by signals from the body’s immune system. Understanding how “c-Rel” affects skin inflammation could lead to new treatments, they said.

  • 31 January 2025
    Zika uses human skin as mosquito magnet to spread virus further

    Zika transmission has been reported more than 90 countries as the spread of the Aedes aegypti mosquito that carries the virus, as well as dengue and chikungunya, has increased over recent years as an effect of climate change and urbanisation. Yet surprisingly little is known about the factors that drive Zika transmission success.  

  • 31 January 2025
    Antibody Treatment Prevents Severe Bird Flu in Monkeys

    A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, University of Pittsburgh and NIH Vaccine Research Center researchers report today in Science.

  • 30 January 2025
    Advanced Brain Circuit-Mapping Technique Reveals New Anxiety Drug Target

    Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target for treating anxiety disorders and related conditions and demonstrates a general strategy, based on a method called photopharmacology, for mapping drug effects on the brain.

  • 30 January 2025
    Changing Cholesterol over Time Tied to Risk of Dementia

    Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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