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  • Bristol Myers Squibb
    26 February 2025

    USFDA accepts Bristol Myers Squibb’s Supplemental Biologics License Application for Opdivo® Plus Yervoy®

    Bristol Myers Squibb announced that the U.S. Food and Drug Administration (FDA) has accepted the supplemental biologics license application for Opdivo nivolumab plus Yervoy ipilimumab as a potential first-line treatment option for adult and pediatric patients 12 years and older with unresectable or metastatic microsatellite instability-high MSI-H or mismatch repair deficient dMMR colorectal cancer
  • 26 February 2025
    UM School of Medicine Dermatology Researchers Discover New Skin Disease Using Innovative Diagnostic Platform

    Utilizing a novel diagnostic test for peripheral blood immunophenotyping, researchers were able to identify the specific sources of inflammation triggering the novel skin disease and reverse symptoms with targeted treatments.

    A significant number of Americans experience chronic inflammatory skin conditions with no pinpointed cause and often no effective treatments beyond symptom management. Now a new study could pave the way for precision-medicine based diagnostic testing and targeted treatment.

  • 26 February 2025
    Hormones may have therapeutic potential to prevent wrinkles, hair graying

    Hormones may be leveraged to treat and prevent signs of aging such as wrinkles and hair graying, according to a new study published in the EndocrineSociety journal Endocrine Reviews.

    Until now, only a limited number of hormones, mainly topical retinoids (retinol and tretinoin) and estrogen which is typically used to treat side effects of menopause, have been used in clinical practice as anti-skin aging compounds. This study reviews a new class of hormones and their anti-aging properties.

  • 26 February 2025
    Research challenges our understanding of cancer predisposition

    New findings question assumptions of cancer formation in individuals with the cancer-predisposition syndrome, neurofibromatosis type 1, and offer hope for a personalised approach to early cancer recognition including for those with similar conditions.

  • 25 February 2025
    Diclofenac increases cardiac risk by 50%
    Diclofenac is having a cardiovascular health risk compared with non-use, paracetamol use, and use of other traditional non-steroidal anti-inflammatory drugs, as per research. The research was conducted by Morten Schmidt and published at the BMJ.
  • 24 February 2025
    FDA Approves First Treatment for Cerebrotendinous Xanthomatosis, a Rare Lipid Storage Disease

    the U.S. Food and Drug Administration approved Ctexli for the treatment of cerebrotendinous xanthomatosis (CTX) in adults. Ctexli is the first FDA-approved drug to treat CTX, a very rare lipid storage disease.

  • 24 February 2025
    Sandoz launches biosimilar Pyzchiva (ustekinumab-ttwe) in the US
    Pyzchiva is a key biosimilar value driver for Sandoz, contributing to the company’s overall growth strategy. The company ranks number one in biosimilars globally and across key markets in Europe. The commercial availability of Pyzchiva, which builds on the US launch of Hyrimoz in July 2023, marks an important step in the Sandoz strategic ambition to become number one in biosimilars in the US.
  • 21 February 2025
    New class of antimalarial drugs discovered
    Malaria remains one of the greatest global health threats. In 2022, there were an estimated 247 million infections and over 600,000 deaths, mostly in sub-Saharan Africa. Innovative research approaches are therefore urgently needed to achieve long-term progress in prevention and treatment.
  • 21 February 2025
    Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
    A new vaccine that boosts immunity against tuberculosis has been shown to be effective in pioneering pre-clinical trials, as part of a successful collaboration between three leading Australian research institutions. A study into the vaccine’s effectiveness, published in eBioMedicine, was led by experts from the Sydney Infectious Diseases Institute at University of Sydney, the Centenary Institute and the Monash Institute of Pharmaceutical Science at Monash University.
  • 20 February 2025
    Dysfunctional B Cells is a new Cancer Immunotherapy Target
    University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood, known as the tertiary lymphoid structure, where they become frustratingly dysfunctional when in close contact with tumors.
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