Pharma News

30 January 2025

Advanced Brain Circuit-Mapping Technique Reveals New Anxiety Drug Target

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target for treating anxiety disorders and related conditions and demonstrates a general strategy, based on a method called photopharmacology, for mapping drug effects on the brain.

30 January 2025

Changing Cholesterol over Time Tied to Risk of Dementia

Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology®, the medical journal of the American Academy of Neurology.

28 January 2025

Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer

Patients with metastatic colorectal cancer harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.

28 January 2025

Iowa researchers study effects of cholesterol-lowering drugs on kidney function

Statins, a class of cholesterol-lowering drugs, have no effect on kidney function, a research team led by the University of Iowa has found. The research team, led by clinical professors Michelle Fravel and Michael Ernst, in the College of Pharmacy, examined the association between statin use in older adults and changes in two important indicators of kidney function estimated glomerular filtration rate and urine albumin-to-creatinine ratio.

24 January 2025

mRNA-activated blood clots could cushion the blow of osteoarthritis

University of Wisconsin-Madison researchers have developed a promising technique for treating osteoarthritis using therapeutic blood clots activated by messenger RNA.

Osteoarthritis is the most common form of arthritis, affecting roughly 33 million adults in the United States, according to the Centers for Disease Control and Prevention. It occurs when cartilage in key joints like the knees and hips deteriorates, causing pain and stiffness and impeding mobility.

24 January 2025

A chain reaction : HIV vaccines can lead to antibodies against antibodies

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

23 January 2025

Achievements under National Health Mission (2021-24) : A Milestone in Improving India’s Public Health Outcomes

The National Health Mission has significantly contributed to improving India's public health outcomes through its relentless efforts in expanding human resources, addressing critical health issues, and fostering an integrated response to health emergencies. Over the last three years, the NHM has driven substantial progress in multiple areas, including maternal and child health, disease elimination, and healthcare infrastructure. The mission’s efforts have been integral to India's health improvements, particularly during the COVID-19 pandemic, and have played a vital role in ensuring more accessible and quality healthcare services across the country.

23 January 2025

Researchers make breakthrough in bioprinting functional human heart tissue

Researchers at University of Galway have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development.

23 January 2025

Green Tea-Based Adhesive Films Show Promise as a Novel Treatment for Oral Mucositis

Green tea shines as a natural powerhouse of antioxidants, with catechins leading the charge among its polyphenols, which protect cells from oxidative stress. These powerful compounds neutralize harmful free radicals generated during cancer treatment. The anti-inflammatory properties of green tea can alleviate oral mucositis, a painful inflammation of the mouth lining often caused by chemotherapy and radiation.

22 January 2025

Researcher Identifies PICH Protein as Key Player in Preventing Chromosome Breakage Linked to Cancer

Researchers at The University of Hong Kong have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer. Led by Professor Gary Ying Wai CHAN from the School of Biological Sciences, Faculty of Science, and Professor Ken Hoi Tang MA from the Department of Pathology, LKS Faculty of Medicine, the research uncovers the vital role of a protein called PICH in preventing genetic errors that can lead to diseases such as cancer. Their findings were recently published in the journal Nucleic Acids Research.

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Advanced Brain Circuit-Mapping Technique Reveals New Anxiety Drug Target

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