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AstraZeneca, Lilly collaborate to test new cancer drug combination

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AstraZeneca and Eli Lilly deepening their collaboration in cancer immunotherapy by testing new drug combinations for treating solid tumours.

Lilly will lead the studies, while both companies will contribute resources. Details of financial arrangements and tumours to be studied were not disclosed.

AstraZeneca's anti-PD-L1 medicine durvalumab would be combined with Lilly molecules, including a TGF-beta kinase inhibitor, a CXCR4 peptide antagonist and an anti-CSF-1R monoclonal antibody, which will also be assessed with AstraZeneca's tremelimumab.

They will also explore other combinations targeting tumour drivers and resistance mechanisms.


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