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1HNMR spectra is different from 13C

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Clinical research courses

Q.1. (a) How 1HNMR spectra is different from 13C? Explain with suitable example.

Ans.1. (a)Difference between 13C-NMR and 1HNMR:

S.NO.

13C-NMR

1HNMR

1

Study of spin changes of carbon nuclei.

Study of spin changes of proton nuclei.

2

Chemical shift ranges between 0-240 ppm.

Chemical shift ranges 0-14 ppm

3

Very fast process

Very low process

4

Pulse-Fourier transform technique is used

Continuous wave method is used.

5

Valve of coupling constant ranges from 125-250 HZ

Ranges from 0-15 HZ

6

Information of total number of protons carbons is obtained.

Information like total number, types of chemical environment of protons is obtained.

7

By peak splitting, possible to interpret protons directly attached to carbon atom

It possible to interpret protons attached to adjacent carbon atom

8

Effect of substitute on substitute on adjacent carbon atom cannot vary the chemical shift.

Substituent alter the chemical shift.

9

It works on frequency sweep

It works on either field sweep or frequency sweep.

Examples:

(ii)


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