FEB 2015 ARTICLE LIST >>
PharmaTutor (February- 2015)
Print-ISSN: 2394 - 6679
e-ISSN: 2347 - 7881
(Volume 3, Issue 2)
Received On: 08/12/2014; Accepted On: 12/12/2014; Published On: 01/02/2015
AUTHORS: Paras Virani1,2*, Parul Jain3, Hasumati Raj2, Vineet Jain2
1Research Scholar 2014, Gujarat Technological University, Gujarat
2Quality assurance department, Shree Dhanvantary Pharmacy College, Kim, Surat
3Quality assurance department, Maliba Pharmacy College, Bardoli, Surat
parasvirani@gmail.com
ABSTRACT: Analytical method is primary requirement of the pharmaceutical industry. In pharmaceutical industry various analytical methods is used like chromatography, spectroscopy method, electrochemical method, ion incorporating method, etc. Irbesartan is classified as an angiotensin II receptor type 1 antagonist. Angiotensin II receptor type 1 antagonists are widely used in treatment of diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Atorvastatin is the most efficacious of the currently available HMG-CoA Reductase inhibitors used in anti lipidemic and also used in atherosclerosis, stroke and cardiac risk. In recently approved new fixed dose combination of Irbesartan and atorvastatin in market of Korea so it require analytical method development which help in industry for new drug delivery system development. This review highlights the role, need and application of various analytical techniques for Irbesartan and atorvastatin combination and their corresponding analytical methods in the pharmaceutical industry.
How to cite this article: P Virani, P Jain, H Raj, V Jain; Need and Application of Analytical Method Development on New Fixed Dose Combination of Irbesartan and Atorvastatin in Pharmaceutical Industry; PharmaTutor; 2015; 3(2); 43-47
[ABSTRACT WITH CITATION] [VIEW AS HTML]
REFERENCES:
1. J. Ermer and McB. Miller. Method validation in pharmaceutical analysis. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2005, 20 – 25.
2. Virani P, Sojitra R, Raj H and Jain V; A review on Irbesartan co administered with Atorvastatin for the treatment of cardiac risk; Journal of Critical Review; 2014; 1(1); 25-28.
3. Antonio ceriello, Roberta assaloni, Roberto da ros, amabile maier, ludovica piconi, Lisa quagliaro, Katherine esposito and Dario giugliano. Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients. Circulation- American heart association. 2013; 111; 2517- 2524.
4. Virani P, Sojitra R, Raj H and Jain V; Irbesartan: A review on analytical method and its determination in pharmaceuticals and biological matrix; Inventi Rapid: Pharm Analysis & Quality Assurance; 2014; 4; 1-6.
5. Virani P, Sojitra R, Raj H and Jain V; Atorvastatin: A review on analytical method and its determination in pharmaceuticals and biological matrix.” Inventi Rapid: Pharm Analysis & Quality Assurance; 2014; 4; 1-6.
6. Hanmi pharmaceutical company limited; Efficacy and safety of Irbesartan and Atorvastatin in hypertension and hyperlipidaemia; March 2013;www.clinicaltrials.gov/show/NCT01442987; 2013
7. D. Allan butterfielda, B. Eugenio baronec, cesare mancusoc; Cholesterol- independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders. Pharmacological research; 2011; 64; 180-186.
8. Charles G. Smith; The Process of New Drug Discovery and Development. Informa Healthcare USA, Inc, 2006; 2(1); 36 – 40.
9. Gorog subrosh; regulatory requirement for analytical method; Journal of Pharmaceutical and Biomedical Analysis; 2005; 931–937.
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